PDGFB 抗体 (AA 89-129)
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Quick Overview for PDGFB 抗体 (AA 89-129) (ABIN5647896)
抗原
See all PDGFB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 89-129
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交叉反应 (详细)
- Expected species reactivity: Human
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids 89-129 (AEPAMIAECKTRTEVFEISRRLIDRTNANFLVWPPCVEVQR) from the human protein were used as the immunogen for the PDGF beta antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the PDGF beta antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the PDGF beta antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- PDGFB (Platelet Derived Growth Factor Subunit B (PDGFB))
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别名
- PDGF beta
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背景
- Platelet-derived growth factor subunit B is a protein that in humans is encoded by the PDGFB gene. The protein encoded by this gene is a member of the platelet-derived growth factor family. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. This gene is mapped to 22q13.1. Growth factor plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. This gene plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA.
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UniProt
- P01127
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
抗原
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