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JAK1 抗体 (AA 78-115)

This anti-JAK1 antibody is a 兔多克隆 antibody detecting JAK1 in WB. Suitable for 人, 小鼠和大鼠.

Western blot testing of 1) rat kidney, 2) mouse kidney and 3) human HeLa lysate with JAK1 antibody at 0. (JAK1 抗体 (AA 78-115))

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产品编号 ABIN5647398

发货至: 中国

Quick Overview for JAK1 抗体 (AA 78-115) (ABIN5647398)

抗原

See all JAK1 抗体

JAK1 (Janus Kinase 1 (JAK1))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

60
6
4
3
3
3
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1

This JAK1 antibody is un-conjugated

应用范围

81
34
31
16
16
15
14
12
11
9
3
2
2
1

Western Blotting (WB)

Discover our top product JAK1 Primary Antibody

抗原表位
17

17

8

6

6

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 78-115

纯化方法

Antigen affinity purified

免疫原

Amino acids 78-115 (FALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTN) from the human protein were used as the immunogen for the JAK1 antibody.

亚型

IgG
anti-Janus Kinase 1 (JAK1) (pTyr1022), (pTyr1023) antibody
JAK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 1 (JAK1) (pTyr1022) antibody
JAK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 1 (JAK1) (AA 960-1040) antibody
JAK1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal unconjugated

anti-Janus Kinase 1 (JAK1) (AA 1020-1024) antibody
JAK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 1 (JAK1) antibody
JAK1 适用: 人, 大鼠 WB, IP 宿主: 小鼠 Monoclonal 7B1-B6-G7 unconjugated

anti-Janus Kinase 1 (JAK1) (AA 172-204), (N-Term) antibody
JAK1 适用: 人 WB 宿主: 兔 Polyclonal RB43809 unconjugated

anti-Janus Kinase 1 (JAK1) (AA 866-899), (C-Term) antibody
JAK1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB43812 unconjugated

anti-Janus Kinase 1 (JAK1) (Ser639) antibody
JAK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 1 (JAK1) (C-Term) antibody
JAK1 适用: 人, 小鼠, 大鼠, 小鸡, 犬, Cow, Pig WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 1 (JAK1) (pTyr1034), (pTyr1035) antibody
JAK1 适用: 人, 小鼠 WB, ELISA, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal dilution of the JAK1 antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL

限制

仅限研究用
缓冲液

0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

储存条件

-20 °C

储存方法

After reconstitution, the JAK1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
抗原

JAK1 (Janus Kinase 1 (JAK1))

别名

JAK1

背景

JAK1 (Janus Kinase 1) is a human tyrosine kinase protein essential for signaling for certain type I and type II cytokines. It is a member of a new class of PTKs that are a large family of proteins characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain--hence the name Janus. The JAK1 gene is mapped to 1p31.3. JAK1 is also important for transducing a signal by type I (IFN-a/b) and type II (IFN-g) interferons, and members of the IL-10 family via type II cytokine receptors. Additionally, Jak1 plays a critical role in initiating responses to multiple major cytokine receptor families. Loss of Jak1 is lethal in neonatal mice, possibly due to difficulties suckling. Expression of JAK1 in cancer cells enables individual cells to contract, potentially allowing them to escape their tumor and metastasize to other parts of the body.

UniProt

P23458

途径

JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response

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