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- 抗原 See all IL1RAP 抗体
- IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))
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抗原表位
- AA 279-313
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IL1RAP antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Antigen affinity purified
- 免疫原
- A portion of amino acids 279-313 from human IL1RAP was used as the immunogen for the IL1RAP antibody.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product IL1RAP Primary Antibody
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anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 420-558) antibody
IL1RAP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 65-249) antibodyIL1RAP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 279-313) antibodyIL1RAP 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB57768 unconjugated
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 1-356) antibodyIL1RAP 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2A3 unconjugated
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 21-356) antibodyIL1RAP 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 484-518) antibodyIL1RAP 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB57769 unconjugated
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (C-Term) antibodyIL1RAP 适用: 人, 小鼠 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 21-356) antibodyIL1RAP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) antibodyIL1RAP 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 251-350) antibodyIL1RAP 适用: 小鼠 ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- The stated application concentrations are suggested starting points. Titration of the IL1RAP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. WB: 1:1000-1:2000
- 限制
- 仅限研究用
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- 缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the IL1RAP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- 抗原
- IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))
- 别名
- IL1RAP (IL1RAP 产品)
- 别名
- IL1RAP antibody, il-1racp antibody, il-racp antibody, il1r3 antibody, C3orf13 antibody, IL-1RAcP antibody, IL1R3 antibody, 6430709H04Rik antibody, AI255955 antibody, AV239853 antibody, IL-1RAcp antibody, Il1racpb antibody, interleukin 1 receptor accessory protein antibody, IL1RAP antibody, il1rap antibody, il-1racp antibody, Il1rap antibody
- 背景
- Coreceptor for IL1RL2 in the IL-36 signaling system (By similarity). Coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1- dependent activation of NF-kappa-B and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Recruits TOLLIP to the signaling complex. Does not bind to interleukin-1 alone, binding of IL1RN to IL1R1, prevents its association with IL1R1 to form a signaling complex. The cellular response is modulated through a non- signaling association with the membrane IL1R2 decoy receptor. Secreted forms (isoforms 2 and 3) associate with secreted ligand- bound IL1R2 and increase the affinity of secreted IL1R2 for IL1B, this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
- UniProt
- Q9NPH3
- 途径
- NF-kappaB Signaling, Growth Factor Binding
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