IL1RAP 抗体 (AA 484-518)
Quick Overview for IL1RAP 抗体 (AA 484-518) (ABIN5647163)
抗原
See all IL1RAP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 484-518
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 484-518 from human IL1RAP was used as the immunogen for the IL1RAP antibody.
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亚型
- Ig Fraction
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anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 65-249) antibody
IL1RAP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 420-558) antibodyIL1RAP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 279-313) antibodyIL1RAP 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB57768 unconjugated
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 1-356) antibodyIL1RAP 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2A3 unconjugated
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 21-356) antibodyIL1RAP 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 484-518) antibodyIL1RAP 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB57769 unconjugated
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (C-Term) antibodyIL1RAP 适用: 人, 小鼠 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 21-356) antibodyIL1RAP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) antibodyIL1RAP 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 21-367) antibodyIL1RAP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting points. Titration of the IL1RAP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. WB: 1:1000-1:2000
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限制
- 仅限研究用
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the IL1RAP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))
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别名
- IL1RAP
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背景
- Coreceptor for IL1RL2 in the IL-36 signaling system (By similarity). Coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1- dependent activation of NF-kappa-B and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Recruits TOLLIP to the signaling complex. Does not bind to interleukin-1 alone, binding of IL1RN to IL1R1, prevents its association with IL1R1 to form a signaling complex. The cellular response is modulated through a non- signaling association with the membrane IL1R2 decoy receptor. Secreted forms (isoforms 2 and 3) associate with secreted ligand- bound IL1R2 and increase the affinity of secreted IL1R2 for IL1B, this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
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UniProt
- Q9NPH3
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途径
- NF-kappaB Signaling, Growth Factor Binding
抗原
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