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Diazepam Binding Inhibitor 抗体 (AA 2-187)

This anti-Diazepam Binding Inhibitor antibody is a 兔 多克隆 antibody detecting Diazepam Binding Inhibitor in WB, FACS 和 IHC (p). Suitable for 人.
产品编号 ABIN5647032
发货至: 中国

Quick Overview for Diazepam Binding Inhibitor 抗体 (AA 2-187) (ABIN5647032)

抗原

See all Diazepam Binding Inhibitor (DBI) 抗体
Diazepam Binding Inhibitor (DBI)

适用

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宿主

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克隆类型

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多克隆

标记

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This Diazepam Binding Inhibitor antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 2-187

    纯化方法

    Antigen affinity purified

    免疫原

    A human recombinant protein corresponding to amino acids S2-I87 was used as the immunogen for the DBI antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the DBI antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL,Flow cytometry: 1-3 μg/10^6 cells

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the DBI antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    Diazepam Binding Inhibitor (DBI)

    别名

    DBI / Diazepam Binding Inhibitor

    背景

    Acyl-CoA-binding protein, also called Diazepam binding inhibitor, is a protein that in humans is encoded by the DBI gene. This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.

    UniProt

    P07108
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