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RAB27A 抗体 (AA 122-221)

This anti-RAB27A antibody is a 小鼠 单克隆 antibody detecting RAB27A in WB, ELISA, IHC (p) 和 RNAi. Suitable for 人. This Primary Antibody has been cited in 8+ publications.
产品编号 ABIN562560
发货至: 中国

Quick Overview for RAB27A 抗体 (AA 122-221) (ABIN562560)

抗原

See all RAB27A 抗体
RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

适用

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宿主

  • 41
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小鼠

克隆类型

  • 43
  • 9
单克隆

标记

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This RAB27A antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)

克隆位点

1G7
  • 抗原表位

    • 8
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    AA 122-221

    原理

    Mouse monoclonal antibody raised against a partial recombinant RAB27A.

    序列

    YCENPDIVLC GNKSDLEDQR VVKEEEAIAL AEKYGIPYFE TSAANGTNIS QAIEMLLDLI MKRMERCVDK SWIPEGVVRS NGHASTDQLS EEKEKGACGC

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    RAB27A (NP_004571, 122 a.a. ~ 221 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Felicetti, De Feo, Coscia, Puglisi, Pedini, Pasquini, Bellenghi, Errico, Pagani, Carè: "Exosome-mediated transfer of miR-222 is sufficient to increase tumor malignancy in melanoma." in: Journal of translational medicine, Vol. 14, pp. 56, (2016) (PubMed).

    Hannafon, Carpenter, Berry, Janknecht, Dooley, Ding: "Exosome-mediated microRNA signaling from breast cancer cells is altered by the anti-angiogenesis agent docosahexaenoic acid (DHA)." in: Molecular cancer, Vol. 14, pp. 133, (2015) (PubMed).

    Cetica, Hackmann, Grieve, Sieni, Ciambotti, Coniglio, Pende, Gilmour, Romagnoli, Griffiths, Aricò: "Patients with Griscelli syndrome and normal pigmentation identify RAB27A mutations that selectively disrupt MUNC13-4 binding." in: The Journal of allergy and clinical immunology, (2014) (PubMed).

    Kimura, Yamaoka, Taniguchi, Okamoto, Takei, Ando, Iwamatsu, Watanabe, Kaibuchi, Ishizaki, Niki: "Activated Cdc42-bound IQGAP1 determines the cellular endocytic site." in: Molecular and cellular biology, Vol. 33, Issue 24, pp. 4834-43, (2013) (PubMed).

    Peinado, Ale?kovi?, Lavotshkin, Matei, Costa-Silva, Moreno-Bueno, Hergueta-Redondo, Williams, García-Santos, Ghajar, Nitadori-Hoshino, Hoffman, Badal, Garcia, Callahan, Yuan, Martins, Skog, Kaplan et al.: "Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. ..." in: Nature medicine, Vol. 18, Issue 6, pp. 883-91, (2012) (PubMed).

    Sanchez-Ruiz, Valitutti, Dupre: "Stepwise maturation of lytic granules during differentiation and activation of human CD8+ T lymphocytes." in: PLoS ONE, Vol. 6, Issue 11, pp. e27057, (2011) (PubMed).

    Neumüller, Hoffmeister, Babica, Prelle, Gegenbauer, Smolenski: "Synaptotagmin-like protein 1 interacts with the GTPase-activating protein Rap1GAP2 and regulates dense granule secretion in platelets." in: Blood, Vol. 114, Issue 7, pp. 1396-404, (2009) (PubMed).

    Kimura, Kaneko, Yamada, Ishihara, Senda, Iwamatsu, Niki: "The GDP-dependent Rab27a effector coronin 3 controls endocytosis of secretory membrane in insulin-secreting cell lines." in: Journal of cell science, Vol. 121, Issue Pt 18, pp. 3092-8, (2008) (PubMed).

  • 抗原

    RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

    别名

    RAB27A

    背景

    Full Gene Name: RAB27A, member RAS oncogene family
    Synonyms: GS2,HsT18676,MGC117246,RAB27,RAM

    基因ID

    5873

    NCBI登录号

    NM_004580

    途径

    Peptide Hormone Metabolism
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