电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

RAB27A 抗体 (AA 122-221)

Cited in 8+ publications. This anti-RAB27A antibody is a 小鼠 单克隆 antibody detecting RAB27A in WB, ELISA, IHC (p) 和 RNAi. Suitable for 人.
产品编号 ABIN562560
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for RAB27A 抗体 (AA 122-221) (ABIN562560)

抗原

See all RAB27A 抗体
RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

适用

  • 63
  • 23
  • 21
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 48
  • 11
  • 3
  • 2
小鼠

克隆类型

  • 41
  • 23
单克隆

标记

  • 36
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This RAB27A antibody is un-conjugated

应用范围

  • 49
  • 25
  • 23
  • 18
  • 15
  • 14
  • 12
  • 5
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)

克隆位点

1G7
  • 抗原表位

    • 8
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 122-221

    原理

    Mouse monoclonal antibody raised against a partial recombinant RAB27A.

    序列

    YCENPDIVLC GNKSDLEDQR VVKEEEAIAL AEKYGIPYFE TSAANGTNIS QAIEMLLDLI MKRMERCVDK SWIPEGVVRS NGHASTDQLS EEKEKGACGC

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    RAB27A (NP_004571, 122 a.a. ~ 221 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Felicetti, De Feo, Coscia, Puglisi, Pedini, Pasquini, Bellenghi, Errico, Pagani, Carè: "Exosome-mediated transfer of miR-222 is sufficient to increase tumor malignancy in melanoma." in: Journal of translational medicine, Vol. 14, pp. 56, (2016) (PubMed).

    Hannafon, Carpenter, Berry, Janknecht, Dooley, Ding: "Exosome-mediated microRNA signaling from breast cancer cells is altered by the anti-angiogenesis agent docosahexaenoic acid (DHA)." in: Molecular cancer, Vol. 14, pp. 133, (2015) (PubMed).

    Cetica, Hackmann, Grieve, Sieni, Ciambotti, Coniglio, Pende, Gilmour, Romagnoli, Griffiths, Aricò: "Patients with Griscelli syndrome and normal pigmentation identify RAB27A mutations that selectively disrupt MUNC13-4 binding." in: The Journal of allergy and clinical immunology, (2014) (PubMed).

    Kimura, Yamaoka, Taniguchi, Okamoto, Takei, Ando, Iwamatsu, Watanabe, Kaibuchi, Ishizaki, Niki: "Activated Cdc42-bound IQGAP1 determines the cellular endocytic site." in: Molecular and cellular biology, Vol. 33, Issue 24, pp. 4834-43, (2013) (PubMed).

    Peinado, Ale?kovi?, Lavotshkin, Matei, Costa-Silva, Moreno-Bueno, Hergueta-Redondo, Williams, García-Santos, Ghajar, Nitadori-Hoshino, Hoffman, Badal, Garcia, Callahan, Yuan, Martins, Skog, Kaplan et al.: "Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. ..." in: Nature medicine, Vol. 18, Issue 6, pp. 883-91, (2012) (PubMed).

    Sanchez-Ruiz, Valitutti, Dupre: "Stepwise maturation of lytic granules during differentiation and activation of human CD8+ T lymphocytes." in: PLoS ONE, Vol. 6, Issue 11, pp. e27057, (2011) (PubMed).

    Neumüller, Hoffmeister, Babica, Prelle, Gegenbauer, Smolenski: "Synaptotagmin-like protein 1 interacts with the GTPase-activating protein Rap1GAP2 and regulates dense granule secretion in platelets." in: Blood, Vol. 114, Issue 7, pp. 1396-404, (2009) (PubMed).

    Kimura, Kaneko, Yamada, Ishihara, Senda, Iwamatsu, Niki: "The GDP-dependent Rab27a effector coronin 3 controls endocytosis of secretory membrane in insulin-secreting cell lines." in: Journal of cell science, Vol. 121, Issue Pt 18, pp. 3092-8, (2008) (PubMed).

  • 抗原

    RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

    别名

    RAB27A

    背景

    Full Gene Name: RAB27A, member RAS oncogene family
    Synonyms: GS2,HsT18676,MGC117246,RAB27,RAM

    基因ID

    5873

    NCBI登录号

    NM_004580

    途径

    Peptide Hormone Metabolism
You are here: