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Pleiotrophin 抗体 (AA 45-154)

Cited in 8+ publications. This anti-Pleiotrophin antibody is a 小鼠 单克隆 antibody detecting Pleiotrophin in WB, ELISA 和 IHC (p). Suitable for 人.
产品编号 ABIN562528
发货至: 中国
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Quick Overview for Pleiotrophin 抗体 (AA 45-154) (ABIN562528)

抗原

See all Pleiotrophin (PTN) 抗体
Pleiotrophin (PTN)

适用

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宿主

  • 102
  • 9
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小鼠

克隆类型

  • 94
  • 21
单克隆

标记

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This Pleiotrophin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

5C3
  • 抗原表位

    • 16
    • 9
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    AA 45-154

    原理

    Mouse monoclonal antibody raised against a partial recombinant PTN.

    序列

    SDCGEWQWSV CVPTSGDCGL GTREGTRTGA ECKQTMKTQR CKIPCNWKKQ FGAECKYQFQ AWGECDLNTA LKTRTGSLKR ALHNAECQKT VTISKPCGKL TKPKPQAESK

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    PTN (NP_002816, 45 a.a. ~ 154 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • He, Boulant, Stanifer, Guo, Nießen, Chen, Felix, Bergmann, Strobel, Schimmack: "The link between menin and pleiotrophin in the tumor biology of pancreatic neuroendocrine neoplasms." in: Cancer science, Vol. 113, Issue 5, pp. 1575-1586, (2022) (PubMed).

    Koutsioumpa, Polytarchou, Courty, Zhang, Kieffer, Mikelis, Skandalis, Hellman, Iliopoulos, Papadimitriou: "Interplay between ?v?3 integrin and nucleolin regulates human endothelial and glioma cell migration." in: The Journal of biological chemistry, Vol. 288, Issue 1, pp. 343-54, (2013) (PubMed).

    Kaspiris, Mikelis, Heroult, Khaldi, Grivas, Kouvaras, Dangas, Vasiliadis, Lioté, Courty, Papadimitriou: "Expression of the growth factor pleiotrophin and its receptor protein tyrosine phosphatase beta/zeta in the serum, cartilage and subchondral bone of patients with osteoarthritis." in: Joint, bone, spine : revue du rhumatisme, Vol. 80, Issue 4, pp. 407-13, (2013) (PubMed).

    Miao, Ding, Zhang, Xiao, Qi, Luo, Di, Tao, Fang: "Pleiotrophin promotes microglia proliferation and secretion of neurotrophic factors by activating extracellular signal-regulated kinase 1/2 pathway." in: Neuroscience research, Vol. 74, Issue 3-4, pp. 269-76, (2012) (PubMed).

    Tsirmoula, Dimas, Hatziapostolou, Lamprou, Ravazoula, Papadimitriou: "Implications of pleiotrophin in human PC3 prostate cancer cell growth in vivo." in: Cancer science, Vol. 103, Issue 10, pp. 1826-32, (2012) (PubMed).

    Mikelis, Lamprou, Koutsioumpa, Koutsioubas, Spyranti, Zompra, Spiliopoulos, Vradis, Katsoris, Spyroulias, Cordopatis, Courty, Papadimitriou: "A peptide corresponding to the C-terminal region of pleiotrophin inhibits angiogenesis in vivo and in vitro." in: Journal of cellular biochemistry, Vol. 112, Issue 6, pp. 1532-43, (2011) (PubMed).

    Koutsioumpa, Hatziapostolou, Mikelis, Koolwijk, Papadimitriou: "Aprotinin stimulates angiogenesis and human endothelial cell migration through the growth factor pleiotrophin and its receptor protein tyrosine phosphatase beta/zeta." in: European journal of pharmacology, Vol. 602, Issue 2-3, pp. 245-9, (2009) (PubMed).

    Mikelis, Sfaelou, Koutsioumpa, Kieffer, Papadimitriou: "Integrin alpha(v)beta(3) is a pleiotrophin receptor required for pleiotrophin-induced endothelial cell migration through receptor protein tyrosine phosphatase beta/zeta." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 5, pp. 1459-69, (2009) (PubMed).

  • 抗原

    Pleiotrophin (PTN)

    别名

    PTN

    背景

    Full Gene Name: pleiotrophin
    Synonyms: HARP,HBGF8,HBNF,NEGF1

    基因ID

    5764

    NCBI登录号

    NM_002825

    途径

    RTK signaling
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