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PDK2 抗体 (AA 187-276)

There are 4+ publications for this product available. The 小鼠 单克隆 anti-PDK2 antibody is suitable to detect PDK2 in samples from 人. It has been validated for WB, ELISA, IHC (p) 和 RNAi.
产品编号 ABIN562160
发货至: 中国
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Quick Overview for PDK2 抗体 (AA 187-276) (ABIN562160)

抗原

See all PDK2 抗体
PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This PDK2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)

克隆位点

2G1
  • 抗原表位

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    AA 187-276

    原理

    Mouse monoclonal antibody raised against a partial recombinant PDK2.

    序列

    HIGSIDPNCN VSEVVKDAYD MAKLLCDKYY MASPDLEIQE INAANSKQPI HMVYVPSHLY HMLFELFKNA MRATVESHES SLILPPIKVM

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    PDK2 (AAH05811, 187 a.a. ~ 276 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Gannon, Ables, Crawford, Lowe, Offield, Magnuson, Wright: "pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis." in: Developmental biology, Vol. 314, Issue 2, pp. 406-17, (2008) (PubMed).

    Babu, Deering, Mirmira: "A feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis." in: Molecular genetics and metabolism, Vol. 92, Issue 1-2, pp. 43-55, (2007) (PubMed).

    Gu, Dubauskaite, Melton: "Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors." in: Development (Cambridge, England), Vol. 129, Issue 10, pp. 2447-57, (2002) (PubMed).

    Ohlsson, Karlsson, Edlund: "IPF1, a homeodomain-containing transactivator of the insulin gene." in: The EMBO journal, Vol. 12, Issue 11, pp. 4251-9, (1993) (PubMed).

  • 抗原

    PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))

    别名

    PDK2

    背景

    Full Gene Name: pyruvate dehydrogenase kinase, isozyme 2
    Synonyms: PDHK2

    基因ID

    5164

    途径

    PI3K-Akt Signaling, RTK signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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