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HSD17B1 抗体 (AA 189-285)

Cited in 3+ publications. This 小鼠 单克隆 anti-HSD17B1 antibody (Clone 2E5) specifically detects HSD17B1 in WB, ELISA 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN561371
发货至: 中国
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Quick Overview for HSD17B1 抗体 (AA 189-285) (ABIN561371)

抗原

See all HSD17B1 抗体
HSD17B1 (Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This HSD17B1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

2E5
  • 抗原表位

    • 9
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    AA 189-285

    原理

    Mouse monoclonal antibody raised against a partial recombinant HSD17B1.

    序列

    VHTAFMEKVL GSPEEVLDRT DIHTFHRFYQ YLAHSKQVFR EAAQNPEEVA EVFLTALRAP KPTLRYFTTE RFLPLLRMRL DDPSGSNYVT AMHREVF

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    HSD17B1 (NP_000404, 189 a.a. ~ 285 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • McNamara, Oguro, Omata, Kikuchi, Guestini, Suzuki, Yang, Abe, Hirakawa, Brown, Takanori, Ohuchi, Sasano: "The presence and impact of estrogen metabolism on the biology of triple-negative breast cancer." in: Breast cancer research and treatment, Vol. 161, Issue 2, pp. 213-227, (2016) (PubMed).

    Inoue, Miki, Abe, Hatori, Hosaka, Kariya, Kakuo, Fujimura, Hachiya, Aiba, Sasano: "The role of estrogen-metabolizing enzymes and estrogen receptors in human epidermis." in: Molecular and cellular endocrinology, Vol. 344, Issue 1-2, pp. 35-40, (2011) (PubMed).

    Chanplakorn, Chanplakorn, Suzuki, Ono, Chan, Miki, Saji, Ueno, Toi, Sasano: "Increased estrogen sulfatase (STS) and 17beta-hydroxysteroid dehydrogenase type 1(17beta-HSD1) following neoadjuvant aromatase inhibitor therapy in breast cancer patients." in: Breast cancer research and treatment, Vol. 120, Issue 3, pp. 639-48, (2010) (PubMed).

  • 抗原

    HSD17B1 (Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1))

    别名

    HSD17B1

    背景

    Full Gene Name: hydroxysteroid (17-beta) dehydrogenase 1
    Synonyms: EDH17B2,EDHB17,HSD17,MGC138140,SDR28C1

    基因ID

    3292

    NCBI登录号

    NM_000413

    途径

    Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis
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