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HSD17B1 抗体 (N-Term)

Cited in 1 publication. The 兔 多克隆 anti-HSD17B1 antibody (ABIN2776958) specifically detects HSD17B1 in WB 和 IHC. The antibody is reactive with 人, 大鼠, 小鼠, Cow, 犬, 马, Pig, 豚鼠 和 兔 samples.
产品编号 ABIN2776958
发货至: 中国
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Quick Overview for HSD17B1 抗体 (N-Term) (ABIN2776958)

抗原

See all HSD17B1 抗体
HSD17B1 (Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1))

适用

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人, 大鼠, 小鼠, Cow, 犬, 马, Pig, 豚鼠, 兔

宿主

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兔

克隆类型

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多克隆

标记

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This HSD17B1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    原理

    HSD17B1 Antibody - N-terminal region

    序列

    MARTVVLITG CSSGIGLHLA VRLASDPSQS FKVYATLRDL KTQGRLWEAA

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 91%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against HSD17B1. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human HSD17B1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41727-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • Tsuchiya, Nakao, Katoh, Sasaki, Hiroshima, Tanaka, Matsunaga, Hanaoka, Tsugane, Ikenoue: "Association between endometriosis and genetic polymorphisms of the estradiol-synthesizing enzyme genes HSD17B1 and CYP19." in: Human reproduction (Oxford, England), Vol. 20, Issue 4, pp. 974-8, (2005) (PubMed).

  • 抗原

    HSD17B1 (Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1))

    别名

    HSD17B1

    背景

    Background Information: HSD17B1 is favors the reduction of estrogens and androgens. It also has 20-alpha-HSD activity. It uses preferentially NADH.

    Gene Name: Hydroxysteroid (17-beta) dehydrogenase 1

    Alternative Symbols: E2DH, HSD17, EDHB17, EDH17B2, SDR28C1, 17-beta-HSD, 20-alpha-HSD

    Protein Name: Estradiol 17-beta-dehydrogenase 1

    分子量

    36kDa

    基因ID

    3292

    NCBI登录号

    NP_000404

    UniProt

    P14061

    途径

    Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis
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