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CTLA4 抗体 (AA 36-161)

This 小鼠 单克隆 anti-CTLA4 antibody (Clone 8B3F8) specifically detects CTLA4 in FACS 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN5611264
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for CTLA4 抗体 (AA 36-161) (ABIN5611264)

抗原

See all CTLA4 抗体
CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

适用

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宿主

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小鼠

克隆类型

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  • 3
单克隆

标记

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This CTLA4 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), ELISA

克隆位点

8B3F8
  • 抗原表位

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    AA 36-161

    原理

    CD152 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human CD152 (AA: 36-161) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

    别名

    CD152

    背景

    This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.

    分子量

    24.6 kDa

    基因ID

    1493

    UniProt

    P16410

    途径

    Cancer Immune Checkpoints
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