PRKAB2 抗体 (AA 1-120)
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- 抗原 See all PRKAB2 抗体
- PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
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抗原表位
- AA 1-120
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PRKAB2 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 原理
- PRKAB2 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human PRKAB2 (AA: 1-120) expressed in E. Coli.
- 克隆位点
- 8F5B2
- 亚型
- IgG1
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anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-120) antibody
PRKAB2 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7A8C3 unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-272) antibodyPRKAB2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G9 unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-272) antibodyPRKAB2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 56-89), (N-Term) antibodyPRKAB2 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-110) antibodyPRKAB2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-272) antibodyPRKAB2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 17-260) antibodyPRKAB2 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 17-260) antibodyPRKAB2 适用: 人 WB, IHC, IF/ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) antibodyPRKAB2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 3-33) antibodyPRKAB2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
- 别名
- PRKAB2 (PRKAB2 产品)
- 背景
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The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.
- 分子量
- 30.3kDa
- 基因ID
- 5565
- HGNC
- 5565
- UniProt
- O43741
- 途径
- AMPK Signaling, Warburg Effect
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