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Axin 抗体 (AA 546-752)

This anti-Axin antibody is a 小鼠 单克隆 antibody detecting Axin in ELISA, ICC 和 FACS. Suitable for 人.
产品编号 ABIN5611198
发货至: 中国

Quick Overview for Axin 抗体 (AA 546-752) (ABIN5611198)

抗原

See all Axin (AXIN1) 抗体
Axin (AXIN1) (Axin 1 (AXIN1))

适用

  • 65
  • 61
  • 28
  • 1
  • 1

宿主

  • 94
  • 5
  • 1
小鼠

克隆类型

  • 95
  • 5
单克隆

标记

  • 38
  • 7
  • 6
  • 6
  • 3
  • 3
  • 3
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  • 3
  • 3
  • 3
  • 3
  • 3
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  • 1
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  • 1
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This Axin antibody is un-conjugated

应用范围

  • 71
  • 39
  • 39
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  • 17
  • 11
  • 10
  • 9
  • 8
  • 5
  • 2
  • 1
ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

克隆位点

4E9F1
  • 抗原表位

    • 15
    • 15
    • 15
    • 8
    • 8
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
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    • 1
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    • 1
    AA 546-752

    原理

    AXIN1 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human AXIN1 (AA: 546-752) expressed in E. Coli.

    亚型

    IgG2b
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/50 - 1/250

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    Axin (AXIN1) (Axin 1 (AXIN1))

    别名

    AXIN1

    背景

    This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Alternative splicing results in multiple transcript variants.

    分子量

    95.6 kDa

    基因ID

    8312

    UniProt

    O15169

    途径

    WNT signaling, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling
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