APAF1 抗体 (AA 1138-1237)
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- 抗原 See all APAF1 抗体
- APAF1 (Apoptotic Peptidase Activating Factor 1 (APAF1))
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抗原表位
- AA 1138-1237
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This APAF1 antibody is un-conjugated
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应用范围
- ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- 原理
- APAF1 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human APAF1 (AA: 1138-1237) expressed in E. Coli.
- 克隆位点
- 2H9A1
- 亚型
- IgG2b
- Top Product
- Discover our top product APAF1 Primary Antibody
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anti-Apoptotic Peptidase Activating Factor 1 (APAF1) (AA 31-350) antibody
APAF1 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Apoptotic Peptidase Activating Factor 1 (APAF1) (AA 13-80) antibodyAPAF1 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Apoptotic Peptidase Activating Factor 1 (APAF1) (AA 1201-1248) antibodyAPAF1 适用: 人, 大鼠, 斑马鱼 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Apoptotic Peptidase Activating Factor 1 (APAF1) (AA 104-415) antibodyAPAF1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Apoptotic Peptidase Activating Factor 1 (APAF1) (C-Term) antibodyAPAF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Apoptotic Peptidase Activating Factor 1 (APAF1) (C-Term) antibodyAPAF1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Apoptotic Peptidase Activating Factor 1 (APAF1) (AA 1-1205) antibodyAPAF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Apoptotic Peptidase Activating Factor 1 (APAF1) (C-Term) antibodyAPAF1 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Apoptotic Peptidase Activating Factor 1 (APAF1) (AA 1-1205) antibodyAPAF1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/100 - 1/500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- APAF1 (Apoptotic Peptidase Activating Factor 1 (APAF1))
- 别名
- APAF1 (APAF1 产品)
- 背景
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This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms.
- 分子量
- 141.8 kDa
- 基因ID
- 317
- 途径
- p53 Pathway, Apoptosis, Caspase Cascade in Apoptosis, Tube Formation, Positive Regulation of Endopeptidase Activity
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