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BTRC 抗体 (AA 24-151)

This anti-BTRC antibody is a 小鼠 单克隆 antibody detecting BTRC in WB, ELISA, IHC 和 FACS. Suitable for 人.
产品编号 ABIN5611131
发货至: 中国

Quick Overview for BTRC 抗体 (AA 24-151) (ABIN5611131)

抗原

See all BTRC 抗体
BTRC (beta-Transducin Repeat Containing (BTRC))

适用

  • 41
  • 16
  • 12
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1

宿主

  • 40
  • 5
小鼠

克隆类型

  • 40
  • 5
单克隆

标记

  • 23
  • 5
  • 5
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BTRC antibody is un-conjugated

应用范围

  • 25
  • 19
  • 17
  • 12
  • 6
  • 4
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

克隆位点

4C5D8
  • 抗原表位

    • 8
    • 6
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 24-151

    原理

    BTRC Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human BTRC (AA: 24-151) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    BTRC (beta-Transducin Repeat Containing (BTRC))

    别名

    BTRC

    背景

    This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class, in addition to an F-box, this protein contains multiple WD-40 repeats. The encoded protein mediates degradation of CD4 via its interaction with HIV-1 Vpu. It has also been shown to ubiquitinate phosphorylated NFKBIA (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha), targeting it for degradation and thus activating nuclear factor kappa-B. Alternatively spliced transcript variants have been described. A related pseudogene exists in chromosome 6.

    分子量

    68.9 kDa

    基因ID

    8945

    UniProt

    Q9Y297

    途径

    Cell Division Cycle, Hedgehog Signaling
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