ATF4 抗体 (AA 171-270)
Quick Overview for ATF4 抗体 (AA 171-270) (ABIN559979)
抗原
See all ATF4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
 - AA 171-270
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原理
 - Mouse monoclonal antibody raised against a partial recombinant ATF4.
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序列
 - SSTPDHSFSL ELGSEVDITE GDRKPDYTAY VAMIPQCIKE EDTPSDNDSG ICMSPESYLG SPQHSPSTRG SPNRSLPSPG VLCGSARPKP YDPPGEKMVA
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交叉反应
 - 人, 小鼠
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产品特性
 - Antibody Reactive Against Recombinant Protein.
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免疫原
 - ATF4 (NP_001666.2, 171 a.a. ~ 270 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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亚型
 - IgG1
 
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应用备注
 - Optimal working dilution should be determined by the investigator.
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限制
 - 仅限研究用
 
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缓冲液
 - In 1x PBS, pH 7.4
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注意事项
 - Aliquot to avoid repeated freezing and thawing.
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储存条件
 - -20 °C
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储存方法
 - Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
 
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                                            : "Decreased vitamin B12 availability induces ER stress through impaired SIRT1-deacetylation of HSF1."    in: Cell death & disease, Vol. 4, pp. e553, (2013)         (PubMed).        
: "A protective role of heme-regulated eIF2? kinase in cadmium-induced toxicity in erythroid cells." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 62, pp. 880-91, (2013) (PubMed).
: "12/15-Lipoxygenase signaling in the endoplasmic reticulum stress response." in: American journal of physiology. Endocrinology and metabolism, Vol. 302, Issue 6, pp. E654-65, (2012) (PubMed).
: "Heme-regulated eIF2? kinase activated Atf4 signaling pathway in oxidative stress and erythropoiesis." in: Blood, Vol. 119, Issue 22, pp. 5276-84, (2012) (PubMed).
: "Calcium channel blocker verapamil enhances endoplasmic reticulum stress and cell death induced by proteasome inhibition in myeloma cells." in: Neoplasia (New York, N.Y.), Vol. 12, Issue 7, pp. 550-61, (2010) (PubMed).
 
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                                            : "Decreased vitamin B12 availability induces ER stress through impaired SIRT1-deacetylation of HSF1."    in: Cell death & disease, Vol. 4, pp. e553, (2013)         (PubMed).        
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- ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))
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别名
 - ATF4
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背景
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                        Full Gene Name: activating transcription factor 4 (tax-responsive enhancer element B67)
Synonyms: CREB-2,CREB2,TAXREB67,TXREB - 
                                            
基因ID
 - 468
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NCBI登录号
 - NM_001675
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途径
 - Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response
 
抗原
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