我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

PARP1 抗体 (AA 1-100)

Name: PARP1 抗体 (AA 1-100)
SKU: ABIN559798
Availability: OutOfStock

Cited in 6+ publications. This anti-PARP1 antibody is a 小鼠单克隆 antibody detecting PARP1 in WB, ELISA 和 IF. Suitable for 人.

PARP1 monoclonal antibody (M01), clone 3G4 Western Blot analysis of PARP1 expression in Hela S3 NE . (PARP1 抗体 (AA 1-100))

Immunofluorescence of monoclonal antibody to PARP1 on HeLa cell. (PARP1 抗体 (AA 1-100))

Detection limit for recombinant GST tagged PARP1 is approximately 0. (PARP1 抗体 (AA 1-100))

ELISA

Western Blot detection against Immunogen (36. (PARP1 抗体 (AA 1-100))

5 images

(6 references)

产品编号 ABIN559798

发货至: 中国

Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PARP1 抗体 (AA 1-100) (ABIN559798)

抗原

See all PARP1 抗体

PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This PARP1 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunofluorescence (IF)

克隆位点

3G4

Discover our top product PARP1 Primary Antibody

抗原表位
32

16

15

15

7

7

7

7

7

7

7

7

7

7

7

6

6

6

5

5

4

4

4

4

3

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-100

原理

Mouse monoclonal antibody raised against a partial recombinant PARP1.

序列

MAESSDKLYR VEYAKSGRAS CKKCSESIPK DSLRMAIMVQ SPMFDGKVPH WYHFSCFWKV GHSIRHPDVE VDGFSELRWD DQQKVKKTAE AGGVTGKGQD

交叉反应

人

产品特性

Antibody Reactive Against Recombinant Protein.

免疫原

PARP1 (AAH37545, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

亚型

IgG2a
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 81-390) antibody
PARP1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) antibody
KO Validated PARP1 适用: 人 WB, ICC, IF, IP, IHC (p), ChIP 宿主: 兔 Polyclonal unconjugated

anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 201-300) antibody
PARP1 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 661-881) antibody
PARP1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 140-220), (Cleaved-Asp214) antibody
PARP1 适用: 人, 小鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 670-858) antibody
PARP1 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) antibody
PARP1 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Monoclonal 8C7 unconjugated Recombinant Antibody

anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (cleaved) antibody
PARP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (N-Term) antibody
PARP1 适用: 人 WB, IHC, 2D-PAGE 宿主: 兔 Polyclonal unconjugated

anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (C-Term) antibody
PARP1 适用: 人 WB, 2D-PAGE 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
缓冲液

In 1x PBS, pH 7.4

注意事项

Aliquot to avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Faraoni, Compagnone, Lavorgna, Angelini, Cencioni, Piras, Panetta, Ottone, Dolci, Venditti, Graziani, Lo-Coco: "BRCA1, PARP1 and ?H2AX in acute myeloid leukemia: Role as biomarkers of response to the PARP inhibitor olaparib." in: Biochimica et biophysica acta, Vol. 1852, Issue 3, pp. 462-72, (2015) (PubMed).

Nicolae, Aho, Vlahos, Choe, De, Karras, Moldovan: "The ADP-ribosyltransferase PARP10/ARTD10 interacts with proliferating cell nuclear antigen (PCNA) and is required for DNA damage tolerance." in: The Journal of biological chemistry, Vol. 289, Issue 19, pp. 13627-37, (2014) (PubMed).

Shen, Oswald, Phelps, Cam, Pelloski, Pang, Houghton: "Regulation of FANCD2 by the mTOR pathway contributes to the resistance of cancer cells to DNA double-strand breaks." in: Cancer research, Vol. 73, Issue 11, pp. 3393-401, (2013) (PubMed).

Luijsterburg, Lindh, Acs, Vrouwe, Pines, van Attikum, Mullenders, Dantuma: "DDB2 promotes chromatin decondensation at UV-induced DNA damage." in: The Journal of cell biology, Vol. 197, Issue 2, pp. 267-81, (2012) (PubMed).

Pines, Vrouwe, Marteijn, Typas, Luijsterburg, Cansoy, Hensbergen, Deelder, de Groot, Matsumoto, Sugasawa, Thoma, Vermeulen, Vrieling, Mullenders: "PARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1." in: The Journal of cell biology, Vol. 199, Issue 2, pp. 235-49, (2012) (PubMed).

Crawford, Yang, Mattaini, Hunter: "The metastasis efficiency modifier ribosomal RNA processing 1 homolog B (RRP1B) is a chromatin-associated factor." in: The Journal of biological chemistry, Vol. 284, Issue 42, pp. 28660-73, (2009) (PubMed).
抗原

PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

别名

PARP1

背景

Full Gene Name: poly (ADP-ribose) polymerase 1
Synonyms: ADPRT,ADPRT1,PARP,PARP-1,PPOL,pADPRT-1

基因ID

142

途径

Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location