MEK2 抗体 (N-Term)
Quick Overview for MEK2 抗体 (N-Term) (ABIN5596868)
抗原
See all MEK2 (MAP2K2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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Supplier Product No.
- 200-301-gn8
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Supplier
- Rockland
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原理
- MEK2 N-Term Antibody
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交叉反应 (详细)
- This protein A purified mouse monoclonal antibody reacts specifically with human MEK2.
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产品特性
- Synonyms: mouse anti-MEK2 Antibody, MAP2K2, MEK, MEK 2, MKK2, PRKMK2 ,CFC4, MEK-2 Antibody
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纯化方法
- Anti-MEK2 is purified from tissue culture supernatant by protein A purification.
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过滤
- Sterile filtered
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免疫原
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Immunogen: Anti-MEK2 Monoclonal Antibody was produced in mice by repeated immunizations with synthetic peptide corresponding to amino acid residues near the N-terminus conjugated to KLH.
Immunogen Type: Conjugated Peptide
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亚型
- IgG2b kappa
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应用备注
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Application Note: Anti-MEK 2 (MOUSE) antibody has been tested in ELISA, PAGE-MAP, and Western Blotting. Specific conditions of reactivity should be optimized by the end user. Expect a band of approximately 44 kDa.
Western Blot Dilution: 1 μg/mL
ELISA Dilution: 1:40,000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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- MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))
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别名
- MAP2K2
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背景
- Background: MEK2 antibodies detect the MEK2 isoform. Mitogen-activated protein kinase kinase 2, also known as MEK2 or MKK2, is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. This pathway also plays a key role in synaptic plasticity in the brain. Activated MEK 2 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase. MEK1 and MEK2 are about 80 % identical to each other, and nearly identical within the kinase domain. The MEK2 antibody is ideal for investigators involved in Neuroscience, Cell Signaling and Cancer Research.
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UniProt
- P36507
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途径
- MAPK Pathway, RTK signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
抗原
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