BLM 抗体 (pSer1290)
Quick Overview for BLM 抗体 (pSer1290) (ABIN5596799)
抗原
See all BLM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer1290
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Supplier Product No.
- 600-401-j55
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Supplier
- Rockland
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原理
- BLM phospho S1290 Antibody
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交叉反应 （详细）
- A BLAST analysis was used to suggest cross-reactivity with human and mouse based on 100 % sequence homology.
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产品特性
- Synonyms: rabbit anti-BLM pS1290 Antibody, DNA helicase, RecQ-like type 2, RECQ2, RECQL3, Bloom syndrome protein
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纯化方法
- Anti-BLM pS1290 was affinity purified from monospecific antiserum by immunoaffinity chromatography and is directed against the phosphorylated form of human S1290 residue.
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免疫原
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Immunogen: Anti-BLM pS1290 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the internal region of human Bloom syndrome protein.
Immunogen Type: Conjugated Peptide
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亚型
- IgG
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anti-Bloom Syndrome RecQ Like Helicase (BLM) (C-Term) antibody
BLM 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Bloom Syndrome RecQ Like Helicase (BLM) (pThr99) antibodyBLM 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bloom Syndrome RecQ Like Helicase (BLM) (AA 1196-1295) antibodyBLM 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E4 unconjugated
anti-Bloom Syndrome RecQ Like Helicase (BLM) (N-Term) antibodyBLM 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bloom Syndrome RecQ Like Helicase (BLM) (AA 1196-1295) antibodyBLM 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Bloom Syndrome RecQ Like Helicase (BLM) (AA 1054-1082), (C-Term) antibodyBLM 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB25943 unconjugated
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应用备注
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Immunohistochemistry Dilution: User Optimized
Application Note: Anti-BLM pS1290 antibody is useful for ELISA, Immunohistochemistry, and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~159 kDa corresponding to the appropriate cell lysate or extract.
Western Blot Dilution: 1 μg/mL
ELISA Dilution: 1: 10,000
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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Reconstitution Volume: 100 μL
Reconstitution Buffer: Restore with deionized water (or equivalent)
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浓度
- 1.1 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
Preservative: None -
储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- BLM (Bloom Syndrome RecQ Like Helicase (BLM))
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别名
- BLM
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背景
- Background: BLM pS1290 product is a member of the RecQ helicase protein family. The protein contains 1417 amino acids, including one ATP binding site, one DEAH box, and two putative nuclear localization signals, as well as phosphorylation sites. BLS protein is known to associate and be phosphorylated by the ATR (ataxia telangiectasia, rad3+) protein, in response to genetic stress. The Bloom's syndrome gene product is thought to play a role in the etiology of two major human health problems, each of which is a very common complication of Bloom's syndrome, namely cancer and diabetes. Anti-BLM pS1290 antibody is ideal for researchers interested in Epigenetics and Nuclear Signaling or DNA Damage & Repair research.
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UniProt
- P54132
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途径
- DNA Damage Repair
抗原
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