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STAT5A 抗体 (2meArg31 (asymetric))

STAT5A 适用: 人 WB, ELISA, DB 宿主: 兔 Polyclonal unconjugated
Rockland
产品编号 ABIN5596750
Supplier Product No.: 600-401-gh5
发货至: 中国
  • 抗原 See all STAT5A 抗体
    STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))
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    2meArg31 (asymetric)
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    克隆类型
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    多克隆
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    This STAT5A antibody is un-conjugated
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    Western Blotting (WB), ELISA, Dot Blot (DB)
    Supplier Product No.
    600-401-gh5
    Supplier
    Rockland
    原理
    STAT5 R31-Me2a Antibody
    交叉反应 (详细)
    This antibody is specific for STAT5 R31/Me2a reacts with human STAT5.
    产品特性
    Synonyms: rabbit anti-STAT5 Asym-dimethyl Arg31 antibody, rabbit anti-STAT5 R31me2a antibody, STAT-5, STAT 5, STAT5A, Signal Transducer and Activator of Transcription 5A antibody, STAT-5A, Transcription factor STAT5A antibody
    纯化方法
    Anti-STAT5 R31/Me2a was affinity purified from monospecific antiserum by immunoaffinity chromatography.
    过滤
    Sterile filtered
    免疫原

    Immunogen: STAT5A [Asym-dimethyl Arg31] affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic monomethylated peptide surrounding Arginine 31 of human STAT.

    Immunogen Type: Conjugated Peptide

    亚型
    IgG
    Top Product
    Discover our top product STAT5A Primary Antibody
  • 应用备注

    Application Note: Anti-STAT5 [Asym-dimethyl Arg31] antibody has been tested by Dot Blot and is useful for Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~90.6 kDa corresponding to STAT5 protein by Western Blotting in the appropriate cell lysate or extract.

    Western Blot Dilution: 1:500

    ELISA Dilution: 1:5000

    Other: User Optimized

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.75 mg/mL
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 30 % Glycerol

    Preservative: 0.05 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))
    别名
    STAT5A (STAT5A 产品)
    背景
    Background: Signal transducer and activator of transcription 5 (Stat5) belongs to a family of cytoplasmic transcription factors that can be activated (phosphorylated) by a cell surface receptor. Phosphorylation at Tyr694 is obligatory for Stat5 activation. Stat5 has two isoforms, Stat5a and Stat5b. Aberrant Stat5 activation has been implicated in the pathogenesis of chronic myelogenous leukemia, prostate and breast cancer and tumor metastasis. Stat5 is localized in the cytoplasm and upon phosphorylation at Y694 is translocated to the nucleus.
    UniProt
    P42229
    途径
    JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation
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