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RPS6KA1 抗体 (C-Term)

RPS6KA1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5596747
发货至: 中国
  • 抗原 See all RPS6KA1 抗体
    RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))
    抗原表位
    • 39
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    C-Term
    适用
    • 197
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    • 90
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    人, 小鼠, 大鼠
    宿主
    • 207
    • 17
    克隆类型
    • 187
    • 38
    多克隆
    标记
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    This RPS6KA1 antibody is un-conjugated
    应用范围
    • 176
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    Western Blotting (WB), ELISA
    交叉反应 (详细)
    A BLAST analysis was used to suggest cross reactivity with RSK1 proteins from human, rat and mouse. Partial reactivity may occur against RSK2 and RSK3 but has not been tested. Reactivity against homologues from other sources is not known.
    纯化方法
    This affinity-purified antibody is directed against the human RSK1 protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification.
    免疫原

    Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a C-terminal region of human RSK1 protein.

    Immunogen Type: Peptide

    亚型
    IgG
    Top Product
    Discover our top product RPS6KA1 Primary Antibody
  • 应用备注

    Application Note: This affinity purified antibody has been tested for use in ELISA, western blot, and immunoprecipitation. Specific conditions for reactivity should be optimized by the end user. Expect a predominant band approximately 88 kDa in size corresponding to RSK1 by western blotting in the appropriate cell lysate or extract.

    Western Blot Dilution: 1:200 - 1:1000

    ELISA Dilution: 1:2,000 - 1:5,000

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液

    Buffer: 0.1 M Tris Chloride, 0.5 M Sodium Chloride, pH 8.0

    Stabilizer: 50 % (v/v) Glycerol

    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))
    别名
    p90 RSK1 (RPS6KA1 产品)
    别名
    HU-1 antibody, MAPKAPK1A antibody, RSK antibody, RSK1 antibody, Rsk1 antibody, p90rsk antibody, rsk antibody, RPS6KA antibody, hu-1 antibody, mapkapk1a antibody, rsk1 antibody, wu:fc56h07 antibody, zgc:152654 antibody, ribosomal protein S6 kinase A1 antibody, ribosomal protein S6 kinase polypeptide 1 antibody, ribosomal protein S6 kinase A1-like antibody, ribosomal protein S6 kinase A1 L homeolog antibody, ribosomal protein S6 kinase a, polypeptide 1 antibody, RPS6KA1 antibody, Rps6ka1 antibody, RPS6KA1L antibody, rps6ka1.L antibody, rps6ka1 antibody
    背景

    Synonyms: 90 kDa ribosomal protein S6 kinase 1 antibody, dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1 antibody, dJ590P13.1 antibody, EC 2.7.11.1 antibody, HU 1 antibody

    Background: RSK1 is a member of a family of 90 kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine/threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsk's appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB. RSK1 is studied in cancer research and is known to inactive tumor supressor complexes and death kinases.

    Gene Name: RPS6KA1, RSK1

    基因ID
    6195
    UniProt
    Q15418
    途径
    MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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