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Periostin 抗体 (full length)

The 小鼠 单克隆 anti-Periostin antibody (Clone Stiny-1) (ABIN5564281) specifically detects Periostin in WB, IHC 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN5564281
发货至: 中国
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Quick Overview for Periostin 抗体 (full length) (ABIN5564281)

抗原

See all Periostin (POSTN) 抗体
Periostin (POSTN)

适用

  • 111
  • 44
  • 38
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 103
  • 26
  • 3
  • 2
  • 1
小鼠

克隆类型

  • 73
  • 62
单克隆

标记

  • 74
  • 18
  • 8
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
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  • 2
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  • 1
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This Periostin antibody is un-conjugated

应用范围

  • 97
  • 59
  • 36
  • 22
  • 15
  • 15
  • 12
  • 10
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA

克隆位点

Stiny-1
  • 抗原表位

    • 9
    • 8
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    full length

    特异性

    Recognizes human and mouse periostin.

    交叉反应

    人, 小鼠

    纯度

    >95 % (SDS-PAGE)

    免疫原

    Full-length human periostin.

    亚型

    IgG1
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    In PBS containing 10 % glycerol.

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.

    有效期

    12 months
  • 抗原

    Periostin (POSTN)

    别名

    Periostin

    背景

    Periostin is a 90- kDa matricellular protein that consists of a typical signal sequence, followed by a cysteine-rich region, an EMI domain (protein-protein interactions), four tandem fasciclin-like domains that are responsible for integrin binding, and a C-terminal region. Periostin was originally isolated as an osteoblast-specific factor that functions as a cell adhesion molecule for pre-osteoblasts and in osteoblast recruitment, attachment and spreading. Periostin is also involved in many fundamental biological processes such as cell proliferation, cell invasion and angiogenesis. Periostin expression is increased by both transforming growth factor beta1 (TGF-beta1) and bone morphogenetic protein 2 (BMP-2). Changes in periostin expression are commonly detected in various cancers and pre-cancerous conditions, and periostin may be involved in regulating cancer cell activities that contribute to tumorigenesis, cancer progression and metastasis. Periostin has shown to be involved in many aspects of allergic inflammation, such as eosinophil recruitment, airway remodeling, development of a Th2 phenotype and increased expression of inflammatory mediators. It is evaluated as a biomarker for bronchial asthma and airway inflammation.
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