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CDK2 抗体

This anti-CDK2 antibody is a 兔 单克隆 antibody detecting CDK2 in WB 和 IHC (p). Suitable for 小鼠 和 大鼠.
产品编号 ABIN5557541
发货至: 中国

Quick Overview for CDK2 抗体 (ABIN5557541)

抗原

See all CDK2 抗体
CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

适用

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小鼠, 大鼠

宿主

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克隆类型

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单克隆

标记

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This CDK2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

2E3
  • 纯化方法

    Purified by Protein A.

    免疫原

    Recombinant human Cdk2 protein, around C-terminal 100aa.

    亚型

    IgG
  • 应用备注

    WB 1:1000-5000
    IHC-P 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存条件

    -20 °C

    储存方法

    Store at -20°C

    有效期

    12 months
  • 抗原

    CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

    别名

    Cdk2

    背景

    The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq, Jul 2008].

    Synonyms: CDKN2, p33(CDK2), Cyclin-dependent kinase 2, Cell division protein kinase 2, p33 protein kinase, CDK2

    基因ID

    1017

    UniProt

    P24941

    途径

    PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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