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Cyclin E1 抗体

This anti-Cyclin E1 antibody is a 兔 单克隆 antibody detecting Cyclin E1 in IHC (p) 和 IF (cc). Suitable for 人 和 小鼠.
产品编号 ABIN5557295
发货至: 中国

Quick Overview for Cyclin E1 抗体 (ABIN5557295)

抗原

See all Cyclin E1 (CCNE1) 抗体
Cyclin E1 (CCNE1)

适用

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人, 小鼠

宿主

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克隆类型

  • 109
  • 58
单克隆

标记

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This Cyclin E1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

克隆位点

4H7
  • 交叉反应

    人, 小鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Synthetic peptide derive from human cyclin e1

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    Cyclin E1 (CCNE1)

    别名

    Cyclin E1

    背景

    Synonyms: Cyclin E1 phospho T77, p-Cyclin E1 phospho T77, Cyclin E1 Thr77, CCNE 1, CCNE,CCNE1,Cyclin E1 antibody Cyclin Es,Cyclin Et,CyclinE, G1/S specic cyclin E.

    Background: Cyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of Cyclin E are only expressed in tumors but not in normal tissue, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in the Cyclin E protein have been implicated as indicators of worse prognosis in various cancers.

    基因ID

    898

    UniProt

    P24864

    途径

    Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Mitotic G1-G1/S Phases
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