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SSH1 抗体 (AA 1032-1044)

This anti-SSH1 antibody is a 小鼠 单克隆 antibody detecting SSH1 in ELISA, FACS 和 ICC. Suitable for 人.
产品编号 ABIN5542669
发货至: 中国

Quick Overview for SSH1 抗体 (AA 1032-1044) (ABIN5542669)

抗原

See all SSH1 抗体
SSH1 (Slingshot Homolog 1 (SSH1))

适用

  • 39
  • 5
  • 3
  • 3

宿主

  • 25
  • 14
小鼠

克隆类型

  • 26
  • 13
单克隆

标记

  • 22
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SSH1 antibody is un-conjugated

应用范围

  • 27
  • 20
  • 6
  • 6
  • 3
  • 3
  • 3
  • 1
ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

克隆位点

1A5C8
  • 抗原表位

    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1032-1044

    原理

    SLINGSHOT-1L Antibody

    纯化方法

    Purified antibody

    免疫原

    Synthesized peptide fragment of human SLINGSHOT-1L (AA: 1032-1044 ) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    SSH1 (Slingshot Homolog 1 (SSH1))

    别名

    SLINGSHOT-1L

    背景

    The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

    分子量

    115.5 kDa

    基因ID

    54434

    UniProt

    Q8WYL5

    途径

    CXCR4-mediated Signaling Events
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