SSH1 抗体 (AA 1032-1044)
Quick Overview for SSH1 抗体 (AA 1032-1044) (ABIN5542669)
抗原
See all SSH1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1032-1044
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原理
- SLINGSHOT-1L Antibody
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纯化方法
- Purified antibody
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免疫原
- Synthesized peptide fragment of human SLINGSHOT-1L (AA: 1032-1044 ) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- SSH1 (Slingshot Homolog 1 (SSH1))
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别名
- SLINGSHOT-1L
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背景
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The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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分子量
- 115.5 kDa
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基因ID
- 54434
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UniProt
- Q8WYL5
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途径
- CXCR4-mediated Signaling Events
抗原
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