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HLA-DRA 抗体 (AA 26-254)

This anti-HLA-DRA antibody is a 小鼠 单克隆 antibody detecting HLA-DRA in WB, FACS, ELISA 和 ICC. Suitable for 人.
产品编号 ABIN5542623
发货至: 中国

Quick Overview for HLA-DRA 抗体 (AA 26-254) (ABIN5542623)

抗原

See all HLA-DRA 抗体
HLA-DRA (HLA Class II DR alpha (HLA-DRA))

适用

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宿主

  • 73
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小鼠

克隆类型

  • 74
  • 73
单克隆

标记

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This HLA-DRA antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)

克隆位点

1C11A5
  • 抗原表位

    • 11
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    • 2
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    AA 26-254

    原理

    HLA-DRA Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human HLA-DRA (AA: 26-254) expressed in E. Coli.

    亚型

    IgG2b
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/100 - 1/500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    HLA-DRA (HLA Class II DR alpha (HLA-DRA))

    别名

    HLA-DRA

    背景

    HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.

    分子量

    28.6 kDa

    基因ID

    3122

    UniProt

    P01903

    途径

    TCR Signaling, CXCR4-mediated Signaling Events, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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