CSF1R 抗体 (AA 20-152)
Quick Overview for CSF1R 抗体 (AA 20-152) (ABIN5542590)
抗原
See all CSF1R 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 20-152
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原理
- CSF1R Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human CSF1R (AA: 20-152) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
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别名
- CSF1R
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背景
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The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction.
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分子量
- 108 kDa
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基因ID
- 1436
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UniProt
- P07333
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途径
- RTK signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
抗原
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