p130 抗体 (AA 939-1139)
Quick Overview for p130 抗体 (AA 939-1139) (ABIN5542553)
抗原
See all p130 (RBL2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 939-1139
-
原理
- RBL2 Antibody
-
纯化方法
- Purified antibody
-
免疫原
- Purified recombinant fragment of human RBL2 (AA: 939-1139) expressed in E. Coli.
-
亚型
- IgG1
-
-
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 165-194), (N-Term) antibody
RBL2 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB31021 unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) antibodyRBL2 适用: 大鼠, 小鼠 IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 100-200) antibodyRBL2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 417-616) antibodyRBL2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) antibodyRBL2 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) antibodyRBL2 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 416-515) antibodyRBL2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 175-189) antibodyRBL2 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 416-515) antibodyRBL2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4D7 unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (C-Term) antibodyRBL2 适用: 人, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA: 1/10000
FCM: 1/200 - 1/400
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
- p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))
-
别名
- RBL2
-
背景
- RBL2 is a Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a tumor suppressor.
-
分子量
- 128.4 kDa
-
基因ID
- 5934
-
UniProt
- Q08999
-
途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
-
