PIK3 gamma 抗体 (AA 1-100)
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Quick Overview for PIK3 gamma 抗体 (AA 1-100) (ABIN5542535)
抗原
See all PIK3 gamma (PIK3CG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-100
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原理
- PIK3CG Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human PIK3CG (AA: 1-100) expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))
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别名
- PIK3CG
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背景
- This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene.
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分子量
- 126.5 kDa
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基因ID
- 5294
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UniProt
- P48736
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途径
- PI3K-Akt Signaling, RTK signaling, AMPK Signaling, TLR signaling, Inositol Metabolic Process, Hepatitis C, VEGF Signaling
抗原
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