NOTCH3 抗体 (AA 47-156)
Our Local Distributor
北京 101111
Quick Overview for NOTCH3 抗体 (AA 47-156) (ABIN5542534)
抗原
See all NOTCH3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 47-156
-
原理
- Notch3 Antibody
-
纯化方法
- Purified antibody
-
免疫原
- Purified recombinant fragment of human Notch3 (AA: 47-156) expressed in E. Coli.
-
亚型
- IgG2a
-
-
-
-
应用备注
- ELISA: 1/10000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
- NOTCH3 (Notch 3 (NOTCH3))
-
别名
- Notch3
-
背景
-
This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
-
分子量
- 243.6 kDa
-
基因ID
- 4854
-
UniProt
- Q9UM47
-
途径
- Notch Signaling
抗原
-