IRAK3 抗体 (AA 454-596)
Quick Overview for IRAK3 抗体 (AA 454-596) (ABIN5542522)
抗原
See all IRAK3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 454-596
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原理
- IRAK3 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human IRAK3 (AA: 454-596) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))
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别名
- IRAK3
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背景
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This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.
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分子量
- 67.8 kDa
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基因ID
- 11213
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UniProt
- Q9Y616
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途径
- TLR signaling, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
抗原
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