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CD27 抗体

This 仓鼠 单克隆 antibody specifically detects CD27 in FACS, IHC (p), IHC (fro) 和 Func. It exhibits reactivity toward 小鼠.
产品编号 ABIN5541980
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD27 抗体 (ABIN5541980)

抗原

See all CD27 抗体
CD27 (CD27 Molecule (CD27))

适用

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小鼠

宿主

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仓鼠

克隆类型

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单克隆

标记

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This CD27 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

克隆位点

LG-3A10
  • 特异性

    Recognizes Mouse CD27 receptor.

    纯化方法

    Protein G Chromatography

    免疫原

    MCD27 tag expressing clones AR0524 and AR0530 from Armenian Hamster spleen.

    亚型

    IgG1
  • 应用备注

    Flow Cytometry: Functional Studies (stimulating). Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections: This clone (LG.3A10) has been reported to work on Paraffin tissue sections.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS Preservatives: None

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CD27 (CD27 Molecule (CD27))

    别名

    cd27

    背景

    CD27 is part of the Tumor Necrosis Factor (TNF) family of receptors and is lymphocyte specific. Murine CD27 is expressed on the great majority of both αβ and γδ T lymphocytes, on a small population of peripheral B cells and on a very small subset of B220+ cells in the bone marrow. Murine CD27 is found on all thymocytes except a subset of CD4-CD8- precursors. There are two known basic functions of CD27 signaling. First, the binding of CD27 to CD70, a protein which is also expressed in T and B cells, provides costimulatory signals in lymphocyte proliferation and immunoglobulin production. Second, the association of CD27 with intracellular Siva, a proapoptotic protein, results in the induction of apoptotic events.

    UniProt

    P41272

    途径

    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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