CD27 抗体
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北京 101111
Quick Overview for CD27 抗体 (ABIN5541980)
抗原
See all CD27 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes Mouse CD27 receptor.
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纯化方法
- Protein G Chromatography
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免疫原
- MCD27 tag expressing clones AR0524 and AR0530 from Armenian Hamster spleen.
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亚型
- IgG1
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应用备注
- Flow Cytometry: Functional Studies (stimulating). Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections: This clone (LG.3A10) has been reported to work on Paraffin tissue sections.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS Preservatives: None
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- CD27 (CD27 Molecule (CD27))
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别名
- cd27
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背景
- CD27 is part of the Tumor Necrosis Factor (TNF) family of receptors and is lymphocyte specific. Murine CD27 is expressed on the great majority of both αβ and γδ T lymphocytes, on a small population of peripheral B cells and on a very small subset of B220+ cells in the bone marrow. Murine CD27 is found on all thymocytes except a subset of CD4-CD8- precursors. There are two known basic functions of CD27 signaling. First, the binding of CD27 to CD70, a protein which is also expressed in T and B cells, provides costimulatory signals in lymphocyte proliferation and immunoglobulin production. Second, the association of CD27 with intracellular Siva, a proapoptotic protein, results in the induction of apoptotic events.
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UniProt
- P41272
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途径
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
抗原
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