14-3-3 sigma/SFN 抗体 (C-Term)
Quick Overview for 14-3-3 sigma/SFN 抗体 (C-Term) (ABIN5541548)
抗原
See all 14-3-3 sigma/SFN (SFN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - C-Term
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特异性
 - This antibody recognizes Human SFN (C-term). Other species not tested.
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纯化方法
 - Protein A column, followed by peptide affinity purification
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免疫原
 - KLH conjugated synthetic peptide between 222-248 amino acids from the C-terminal region of Human SFN.
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亚型
 - Ig Fraction
 
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应用备注
 - Western blotting: 1/1000. Immunohistochemistry on Paraffin Sections: 1/10-1/50. Flow Cytometry: Immunofluorescence:
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限制
 - 仅限研究用
 
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状态
 - Liquid
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缓冲液
 - PBS Preservatives: 0.09 % (W/V) Sodium Azide
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C,-20 °C
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储存方法
 - Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
 - 12 months
 
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- 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
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别名
 - 14-3-3 protein sigma,sfn
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背景
 - Members of the 14-3-3 family of proteins are highly conserved proteins, localized in neurons, and are axolly transported to the nerve termils. They are also present, at lower levels, in various other eukaryotic tissues. 14-3-3 proteins appear to play important roles in a variety of sigl transduction pathways, including those involved in cell cycle regulation and cell survival. Because 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in sigling pathways mediated by serine/threonine protein kises. Evidence indicates 14-3-3 is required for Raf 1 kise activity and phosphorylation among many other functions.
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UniProt
 - P31947
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途径
 - p53 Pathway, Myometrial Relaxation and Contraction
 
抗原
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