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CEACAM5 抗体

This anti-CEACAM5 antibody is a 小鼠 单克隆 antibody detecting CEACAM5 in FACS, IF, WB, IHC (fro), EIA 和 ICC. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN5541179
发货至: 中国

Quick Overview for CEACAM5 抗体 (ABIN5541179)

抗原

See all CEACAM5 抗体
CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

适用

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宿主

  • 93
  • 46
  • 6
小鼠

克隆类型

  • 106
  • 35
  • 2
单克隆

标记

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This CEACAM5 antibody is un-conjugated

应用范围

  • 84
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Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Immunocytochemistry (ICC)

克隆位点

26-3-13
  • 特异性

    This antibody recognizes exclusively CECAM5.

    纯化方法

    Protein G Chromatography

    免疫原

    Extracted protein of CEACAM5. Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells

    亚型

    IgG1
  • 应用备注

    ELISA: 1/200-1/400. Cell based ELISA with intakt, transiently transfected cells: 1/200. Flow Cytometry: 1.2 μg/10 6 cells. Immunofluorescence: 1/200. Western blot: 4 μg/mL. Immunohistochemistry on Cryo -Sections: 1-2 μg/10

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.2 without preservatives

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    有效期

    12 months
  • Schmitter, Agerer, Peterson, Munzner, Hauck: "Granulocyte CEACAM3 is a phagocytic receptor of the innate immune system that mediates recognition and elimination of human-specific pathogens." in: The Journal of experimental medicine, Vol. 199, Issue 1, pp. 35-46, (2004) (PubMed).

  • 抗原

    CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

    别名

    cd66e,ceacam5

    背景

    CEACAM5 (CEA-related cell adhesion molecule 5, CEA) belongs to the carcinoembryonic antigen (CEA) gene family (1,2). It encodes a glycosyl phosphatidyl inositol (GPI)-linked glycoprotein with a Mr of 180,000-200,000 which is most strongly expressed on epithelial cells of the fetal and adult colon and to a minor extent on epithelial cells of the stomach and sweat glands, squamous epithelial cell of the tongue, esophagus and cervix. CEACAM5 is used as a tumor marker for early detection of recurrent disease due to its expression in adenocarcinomas of the colon, lung, breast, stomach and pancreas and in mucinous ovarian carcinomas (3). Like all members of the CEACAM family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by six immunoglobulin constant-like A (A1, A2, A3) and B domains (B1, B2, B3).

    UniProt

    P06731
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