CCR2 抗体
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北京 101111
Quick Overview for CCR2 抗体 (ABIN5540857)
抗原
See all CCR2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody detects
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纯化方法
- Protein G
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免疫原
- DNA vaccine
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亚型
- IgG2a
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应用备注
- Immunohistochemistry on paraffin sections: 4-8-μg/mL (1/50-1/100) Pretreatment with proteinase K required.
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限制
- 仅限研究用
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缓冲液
- Phosphate buffered saline pH 7.2 (PBS) Preservatives: 0.1 % Kathon Stabilizers: 5 mg/mL bovine serum albumin (BSA)
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储存条件
- 4 °C,-20 °C
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储存方法
- Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
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别名
- cd192,ccr2
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背景
- CCR2B is a 374 amino acid protein that belongs to the G - protein coupled receptor 1 family with seven transmembrane domains. It mediates the chemotactic properties of monocyte chemoattractant protein 1 (MCP - 1) which is secreted by endothelial and epithelial cells, vascular smooth muscle and hematopoietic cells. MCP - 1 is a potent chemoattractant for monocytes and lymphocytes. It is responsible for monocyte infiltration in a variety of chronic inflammatory diseases.
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UniProt
- P41597
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途径
- cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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