SYN1 抗体
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北京 101111
Quick Overview for SYN1 抗体 (ABIN5540676)
抗原
See all SYN1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Specific for the ~78k synapsin I doublet in Western blots of rat brain extracts. Immunolabeling blocked by preadsorption of antibody with the protein used to generate the antibody.
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纯化方法
- Affinity purification using a column to which the native protein was coupled
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免疫原
- Native protein purified from bovine brain
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亚型
- Ig Fraction
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应用备注
- Western blot: 1/1000. Immunohistochemistry / immunoflourescence: 1:1000. Immunoprecipitation: 2 μL per 200 μg lysate.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg BSA per ml and 50 % glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- SYN1 (Synapsin I (SYN1))
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别名
- synapsin-1
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背景
- Synapsin I plays a key role in synaptic plasticity in brain (Feng et al., 2002 Nayak et al., 1996). This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. In addition to its role in plasticity, the expression of synapsin I is a precise indicator of synapse formation (Moore and Bernstein, 1989 Stone et al., 1994). Thus, synapsin I immunocytochemistry provides a valuable tool for the study of synaptogenesis. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation (Jovanovic et al., 2001 Kao et al., 2002).
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UniProt
- P17599
抗原
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