IL13 Receptor alpha 1 抗体 (Extracellular Domain)
Quick Overview for IL13 Receptor alpha 1 抗体 (Extracellular Domain) (ABIN5540414)
抗原
See all IL13 Receptor alpha 1 (IL13RA1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
 - Extracellular Domain
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特异性
 - Recognizes IL13 Receptor (IL13-R).
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纯化方法
 - Affinity Chromatography on Protein G
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免疫原
 - Genetic immunization with cDNA encoding Human IL13-R alpha 1 (extracellular domain). Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells.
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亚型
 - IgG1
 
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应用备注
 - Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400. Flow cytometry: 1.2 μg/10 6 cells. Immunofluorescence: 1 μg/10 Specific inhibition of IL-13-dependent proliferation of TF-1 cells by GM-1E7 (See Figure.3).
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限制
 - 仅限研究用
 
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状态
 - Liquid
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缓冲液
 - Phosphate buffered saline, pH 7.2 without preservatives
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储存液
 - Without preservative
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储存条件
 - 4 °C,-20 °C
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储存方法
 - Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
 - 12 months
 
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- IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))
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别名
 - cd213a1,il13ra1
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背景
 - Interleukin 13 (IL-13) is a T cell derived cytokine involved in the regulation of inflammatory and im-mune responses. IL-13Ra1 together with IL-4Ra forms a functional receptor for both IL-4 and IL-13, which is why these two cytokines share many of their biological activities. The receptor is found on human B cells, monocytes and endothelial cells. However, no functional receptor is expressed on T cells, which explains why IL-13, in contrast to IL-4, fails to induce TH2-cell differentiation
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UniProt
 - P78552
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途径
 - JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
 
抗原
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