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IL13 Receptor alpha 1 抗体 (Extracellular Domain)

This anti-IL13 Receptor alpha 1 antibody is a 小鼠 单克隆 antibody detecting IL13 Receptor alpha 1 in IF, ICC, FACS 和 EIA. Suitable for 人.
产品编号 ABIN5540414
发货至: 中国

Quick Overview for IL13 Receptor alpha 1 抗体 (Extracellular Domain) (ABIN5540414)

抗原

See all IL13 Receptor alpha 1 (IL13RA1) 抗体
IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

适用

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  • 1
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  • 1
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宿主

  • 70
  • 12
  • 2
小鼠

克隆类型

  • 61
  • 23
单克隆

标记

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This IL13 Receptor alpha 1 antibody is un-conjugated

应用范围

  • 55
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Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

克隆位点

GM1E7
  • 抗原表位

    • 8
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
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    • 2
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    • 1
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    • 1
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    • 1
    • 1
    • 1
    Extracellular Domain

    特异性

    Recognizes IL13 Receptor (IL13-R).

    纯化方法

    Affinity Chromatography on Protein G

    免疫原

    Genetic immunization with cDNA encoding Human IL13-R alpha 1 (extracellular domain). Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells.

    亚型

    IgG1
  • 应用备注

    Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400. Flow cytometry: 1.2 μg/10 6 cells. Immunofluorescence: 1 μg/10 Specific inhibition of IL-13-dependent proliferation of TF-1 cells by GM-1E7 (See Figure.3).

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Phosphate buffered saline, pH 7.2 without preservatives

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

    别名

    cd213a1,il13ra1

    背景

    Interleukin 13 (IL-13) is a T cell derived cytokine involved in the regulation of inflammatory and im-mune responses. IL-13Ra1 together with IL-4Ra forms a functional receptor for both IL-4 and IL-13, which is why these two cytokines share many of their biological activities. The receptor is found on human B cells, monocytes and endothelial cells. However, no functional receptor is expressed on T cells, which explains why IL-13, in contrast to IL-4, fails to induce TH2-cell differentiation

    UniProt

    P78552

    途径

    JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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