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IL13 Receptor alpha 1 抗体 (Extracellular Domain)

IL13RA1 适用: 人 IF, ICC, FACS, EIA 宿主: 小鼠 Monoclonal GM1C8 unconjugated
产品编号 ABIN5540413
发货至: 中国
  • 抗原 See all IL13 Receptor alpha 1 (IL13RA1) 抗体
    IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))
    抗原表位
    • 8
    • 8
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Extracellular Domain
    适用
    • 73
    • 25
    • 16
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 67
    • 11
    小鼠
    克隆类型
    • 59
    • 19
    单克隆
    标记
    • 40
    • 13
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This IL13 Receptor alpha 1 antibody is un-conjugated
    应用范围
    • 51
    • 31
    • 18
    • 12
    • 8
    • 8
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    特异性
    Clone GM1C8 recognises IL-13Rα1 transiently expressed on the cell surface of transfected BOSC cells as well as the native protein on monocytes (W. Luttmann, unpublished data). Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells. Species: Human.
    纯化方法
    Protein G chromatography
    免疫原
    cDNA of the human IL-13Ralpha1 chain extracellular domain (U62858).
    克隆位点
    GM1C8
    亚型
    IgG1
    Top Product
    Discover our top product IL13RA1 Primary Antibody
  • 应用备注
    Flow cytometry: 1.2 μg/10 6 cells. The antibody is routinely tested by on BOSC cells transiently transfected with an IL-13Rα1 expression vector. Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400. It is expected that the antibody will be suited for all applications where recognition of the native protein is required.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.2 Preservatives: 0.01 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
    有效期
    12 months
  • Bizzarro, Fontanella, Carratù, Belvedere, Marfella, Parente, Petrella: "Annexin A1 N-terminal derived peptide Ac2-26 stimulates fibroblast migration in high glucose conditions." in: PLoS ONE, Vol. 7, Issue 9, pp. e45639, (2013) (PubMed).

    Thomas, Zhu, Schnaar, Alves, Konstantopoulos: "Carcinoembryonic antigen and CD44 variant isoforms cooperate to mediate colon carcinoma cell adhesion to E- and L-selectin in shear flow." in: The Journal of biological chemistry, Vol. 283, Issue 23, pp. 15647-55, (2008) (PubMed).

    Kunii, Nemoto, Kanaya, Tsubahara, Shimauchi: "Expression of CD13/aminopeptidase N on human gingival fibroblasts and up-regulation upon stimulation with interleukin-4 and interleukin-13." in: Journal of periodontal research, Vol. 40, Issue 2, pp. 138-46, (2005) (PubMed).

    Bade, Lohrmann, ten Brinke, Wolbink, Wolbink, ten Berge, Virchow, Luttmann, Hack: "Detection of soluble human granzyme K in vitro and in vivo." in: European journal of immunology, Vol. 35, Issue 10, pp. 2940-8, (2005) (PubMed).

  • 抗原
    IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))
    别名
    cd213a1,il13ra1 (IL13RA1 产品)
    别名
    CD213A2 antibody, CT19 antibody, IL-13R antibody, IL13BP antibody, CD213A1 antibody, IL-13Ra antibody, NR4 antibody, AI882074 antibody, CD213a1 antibody, IL-13r[a] antibody, Il13ra antibody, IL13RA1 antibody, il-13ra1 antibody, si:ch211-150g2.2 antibody, interleukin 13 receptor subunit alpha 2 antibody, interleukin 13 receptor subunit alpha 1 antibody, interleukin 13 receptor, alpha 1 antibody, interleukin 13 receptor, alpha 1-like antibody, IL13RA2 antibody, IL13RA1 antibody, Il13ra1 antibody, il13ra1 antibody, LOC100360218 antibody
    背景
    Interleukin 13 (IL-13) is a T cell derived cytokine involved in the regulation of inflammatory and im-mune responses. IL-13Rα1 together with IL-4Rα forms a functional receptor for both IL-4 and IL-13, which is why these two cytokines share many of their biological activities. The receptor is found on human B cells, monocytes and endothelial cells. However, no functional receptor is expressed on T cells, which explains why IL-13, in contrast to IL-4, fails to induce TH2-cell differentiation.
    UniProt
    P78552
    途径
    JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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