IL13 Receptor alpha 1 抗体 (Extracellular Domain)
(4 references)Quick Overview for IL13 Receptor alpha 1 抗体 (Extracellular Domain) (ABIN5540413)
抗原
See all IL13 Receptor alpha 1 (IL13RA1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Extracellular Domain
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特异性
- Clone GM1C8 recognises IL-13Rα1 transiently expressed on the cell surface of transfected BOSC cells as well as the native protein on monocytes (W. Luttmann, unpublished data). Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells. Species: Human.
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纯化方法
- Protein G chromatography
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免疫原
- cDNA of the human IL-13Ralpha1 chain extracellular domain (U62858).
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亚型
- IgG1
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anti-Interleukin 13 Receptor, alpha 1 (IL13RA1) (AA 22-343) antibody
IL13RA1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 8A3E3 unconjugated
anti-Interleukin 13 Receptor, alpha 1 (IL13RA1) (Extracellular Domain) antibodyIL13RA1 适用: 人 ELISA, FACS, cELISA, Anta 宿主: 小鼠 Monoclonal GM-1E7 unconjugated
anti-Interleukin 13 Receptor, alpha 1 (IL13RA1) (AA 203-376) antibodyIL13RA1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 Receptor, alpha 1 (IL13RA1) (AA 1-427) antibodyIL13RA1 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 13 Receptor, alpha 1 (IL13RA1) (C-Term) antibodyIL13RA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 Receptor, alpha 1 (IL13RA1) (AA 371-420) antibodyIL13RA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 Receptor, alpha 1 (IL13RA1) antibodyIL13RA1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 Receptor, alpha 1 (IL13RA1) (AA 22-234) antibodyIL13RA1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 Receptor, alpha 1 (IL13RA1) antibodyIL13RA1 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 Receptor, alpha 1 (IL13RA1) (AA 1-427) antibodyIL13RA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F5 unconjugated
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应用备注
- Flow cytometry: 1.2 μg/10 6 cells. The antibody is routinely tested by on BOSC cells transiently transfected with an IL-13Rα1 expression vector. Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400. It is expected that the antibody will be suited for all applications where recognition of the native protein is required.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.2 Preservatives: 0.01 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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: "Annexin A1 N-terminal derived peptide Ac2-26 stimulates fibroblast migration in high glucose conditions." in: PLoS ONE, Vol. 7, Issue 9, pp. e45639, (2013) (PubMed).
: "Carcinoembryonic antigen and CD44 variant isoforms cooperate to mediate colon carcinoma cell adhesion to E- and L-selectin in shear flow." in: The Journal of biological chemistry, Vol. 283, Issue 23, pp. 15647-55, (2008) (PubMed).
: "Expression of CD13/aminopeptidase N on human gingival fibroblasts and up-regulation upon stimulation with interleukin-4 and interleukin-13." in: Journal of periodontal research, Vol. 40, Issue 2, pp. 138-46, (2005) (PubMed).
: "Detection of soluble human granzyme K in vitro and in vivo." in: European journal of immunology, Vol. 35, Issue 10, pp. 2940-8, (2005) (PubMed).
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: "Annexin A1 N-terminal derived peptide Ac2-26 stimulates fibroblast migration in high glucose conditions." in: PLoS ONE, Vol. 7, Issue 9, pp. e45639, (2013) (PubMed).
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- IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))
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别名
- cd213a1,il13ra1
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背景
- Interleukin 13 (IL-13) is a T cell derived cytokine involved in the regulation of inflammatory and im-mune responses. IL-13Rα1 together with IL-4Rα forms a functional receptor for both IL-4 and IL-13, which is why these two cytokines share many of their biological activities. The receptor is found on human B cells, monocytes and endothelial cells. However, no functional receptor is expressed on T cells, which explains why IL-13, in contrast to IL-4, fails to induce TH2-cell differentiation.
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UniProt
- P78552
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途径
- JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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