Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) 抗体
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Quick Overview for Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) 抗体 (ABIN5540300)
抗原
See all Dual Specificity Phosphatase 3 (DUSP3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-185
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纯化方法
- Protein-A affinity chromatography
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免疫原
- Recombinant human DUSP3 (1-185aa) purified from E. coli.
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亚型
- IgG2b
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应用备注
- The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution for Western blot analysis is 1:3000.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. In Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- Dual Specificity Phosphatase 3 (DUSP3)
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别名
- dusp3
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背景
- DUSP3, also known as Dual specificity protein phosphatase 3, is ictivate their target kises by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kise superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kises, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.
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UniProt
- P51452
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途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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