PD-1 抗体
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北京 101111
Quick Overview for PD-1 抗体 (ABIN5540157)
抗原
See all PD-1 (PDCD1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Reactive with recombinant Human Programmed Cell Death-1 (PD-1). Reactivity with natural PD-1 has not been evaluated.
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- 40kDa recombinant Human Programmed Cell Death-1 (PD-1).
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亚型
- IgG1
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anti-Programmed Cell Death 1 (PDCD1) (AA 201-288) antibody
PDCD1 适用: 人, 小鼠, 大鼠 FACS, WB, ELISA, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 1 (PDCD1) (AA 41-132) antibodyPDCD1 适用: 人 IHC, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 1 (PDCD1) (AA 192-288) antibodyPDCD1 适用: 人 FACS, WB, ELISA 宿主: 小鼠 Monoclonal 3B3D9 unconjugated
anti-Programmed Cell Death 1 (PDCD1) (AA 192-288) antibodyPDCD1 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 8G5B12 unconjugated
anti-Programmed Cell Death 1 (PDCD1) (AA 84-117), (N-Term) antibodyPDCD1 适用: 小鼠, 大鼠 FACS, IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 1 (PDCD1) (AA 21-170) antibodyPDCD1 适用: 人 FACS, WB, ELISA 宿主: 小鼠 Monoclonal 1D6F6 unconjugated
anti-Programmed Cell Death 1 (PDCD1) (AA 21-170) antibodyPDCD1 适用: 人 FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 3E12A10 unconjugated
anti-Programmed Cell Death 1 (PDCD1) antibodyPDCD1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal PDCD1-2720 unconjugated
anti-Programmed Cell Death 1 (PDCD1) (AA 21-170) antibodyPDCD1 适用: 人 IHC, WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 1 (PDCD1) (AA 1-288) antibodyPDCD1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Indirect ELISA. Western Blot.
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限制
- 仅限研究用
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缓冲液
- 0.01M PBS, pH 7.2 without preservatives
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
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别名
- cd279,pd1
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背景
- Programmed Cell Death-1 (PD-1), also called CD279, is a 288 amino acid cell surface protein that belongs to the immunoglobulin superfamily. The protein is expressed on T cells, B cells and macrophages. When PD-1 is joined with its ligand (CD274 or B7-H1), the immune cell's activation and effector function are attenuated. Research suggested that PD1 pathway is mainly involved with attenuation at periphery sites while the B7/CTLA-4 pathway is primarily involved with the attenuation of the activation of immune cells in secondary lymphoid organs. PD-1 pathway is implicated with cancer's immune-evasion, autoimmunity, and Listeria monocytogenes infection.
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UniProt
- Q15116
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途径
- Cancer Immune Checkpoints
抗原
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