Programmed Cell Death 1 抗体
(Programmed Cell Death 1 (PDCD1))
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008].
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Independently Validated
Latest Publications for our Programmed Cell Death 1 抗体
: "Evaluation of costimulatory molecules in dogs with B cell high grade lymphoma." in: PLoS ONE, Vol. 13, Issue 7, pp. e0201222, (2019) (PubMed).
: "Immune Activation and Benefit From Avelumab in EBV-Positive Gastric Cancer." in: Journal of the National Cancer Institute, Vol. 110, Issue 3, pp. 316-320, (2019) (PubMed).
: "Low levels of SIV-specific CD8+ T cells in germinal centers characterizes acute SIV infection." in: PLoS pathogens, Vol. 15, Issue 3, pp. e1007311, (2019) (PubMed).
: "Tumor-derived exosomal HMGB1 promotes esophageal squamous cell carcinoma progression through inducing PD1+ TAM expansion." in: Oncogenesis, Vol. 8, Issue 3, pp. 17, (2019) (PubMed).
: "IL-17C-mediated innate inflammation decreases the response to PD-1 blockade in a model of Kras-driven lung cancer." in: Scientific reports, Vol. 9, Issue 1, pp. 10353, (2019) (PubMed).
: "Hepatic expression of programmed death-1 (PD-1) and its ligand, PD-L1, in children with autoimmune hepatitis: relation to treatment response." in: Clinical and experimental hepatology, Vol. 5, Issue 3, pp. 256-264, (2019) (PubMed).
: "Non-conventional Inhibitory CD4+Foxp3-PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity." in: Cancer cell, Vol. 33, Issue 6, pp. 1017-1032.e7, (2019) (PubMed).
: "Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability." in: Nature communications, Vol. 8, Issue 1, pp. 1323, (2018) (PubMed).
: "89Zr-labeled nivolumab for imaging of T-cell infiltration in a humanized murine model of lung cancer." in: European journal of nuclear medicine and molecular imaging, Vol. 45, Issue 1, pp. 110-120, (2018) (PubMed).
: "Quantitative Multiplexed Imaging Analysis Reveals a Strong Association between Immunogen-Specific B Cell Responses and Tonsillar Germinal Center Immune Dynamics in Children after Influenza ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 2, pp. 538-550, (2018) (PubMed).
: "Immune Activation and Benefit From Avelumab in EBV-Positive Gastric Cancer." in: Journal of the National Cancer Institute, Vol. 110, Issue 3, pp. 316-320, (2019) (PubMed).
: "Low levels of SIV-specific CD8+ T cells in germinal centers characterizes acute SIV infection." in: PLoS pathogens, Vol. 15, Issue 3, pp. e1007311, (2019) (PubMed).
: "Tumor-derived exosomal HMGB1 promotes esophageal squamous cell carcinoma progression through inducing PD1+ TAM expansion." in: Oncogenesis, Vol. 8, Issue 3, pp. 17, (2019) (PubMed).
: "IL-17C-mediated innate inflammation decreases the response to PD-1 blockade in a model of Kras-driven lung cancer." in: Scientific reports, Vol. 9, Issue 1, pp. 10353, (2019) (PubMed).
: "Hepatic expression of programmed death-1 (PD-1) and its ligand, PD-L1, in children with autoimmune hepatitis: relation to treatment response." in: Clinical and experimental hepatology, Vol. 5, Issue 3, pp. 256-264, (2019) (PubMed).
: "Non-conventional Inhibitory CD4+Foxp3-PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity." in: Cancer cell, Vol. 33, Issue 6, pp. 1017-1032.e7, (2019) (PubMed).
: "Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability." in: Nature communications, Vol. 8, Issue 1, pp. 1323, (2018) (PubMed).
: "89Zr-labeled nivolumab for imaging of T-cell infiltration in a humanized murine model of lung cancer." in: European journal of nuclear medicine and molecular imaging, Vol. 45, Issue 1, pp. 110-120, (2018) (PubMed).
: "Quantitative Multiplexed Imaging Analysis Reveals a Strong Association between Immunogen-Specific B Cell Responses and Tonsillar Germinal Center Immune Dynamics in Children after Influenza ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 2, pp. 538-550, (2018) (PubMed).
Aliases for Programmed Cell Death 1 抗体
programmed cell death 1 (PDCD1) 抗体programmed cell death 1 (Pdcd1) 抗体
CD279 抗体
hPD-1 抗体
hPD-l 抗体
Ly101 抗体
PD-1 抗体
PD1 抗体
Pdc1 抗体
SLEB2 抗体
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