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Integrin beta 3 抗体 (APC)

This anti-Integrin beta 3 antibody is a 小鼠 单克隆 antibody detecting Integrin beta 3 in FACS. Suitable for 人 和 灵长类.
产品编号 ABIN5540114
发货至: 中国

Quick Overview for Integrin beta 3 抗体 (APC) (ABIN5540114)

抗原

See all Integrin beta 3 (ITGB3) 抗体
Integrin beta 3 (ITGB3)

适用

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人, 灵长类

宿主

  • 132
  • 91
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小鼠

克隆类型

  • 120
  • 114
单克隆

标记

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This Integrin beta 3 antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)

克隆位点

VIPL2
  • 特异性

    This antibody recognizes CD61, a 90-110 kDa transmembrane glycoprotein of integrin family, expressed on platelets, megacaryocytes, osteoclasts, endothelial cells and other cell types, including leucocytes and smooth muscle cells.

    亚型

    IgG1
  • 应用备注

    Flow Cytometry analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10 6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

    限制

    仅限研究用
  • 状态

    Liquid

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    PStore the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    Integrin beta 3 (ITGB3)

    别名

    cd61,itgb3

    背景

    CD61 (beta3 integrin) is a transmembrane glycoprotein, which associates with CD41 or CD51 Molecules to form heterodimeric adhesion receptores. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. It binds to fibronectin, fibrinogen and von Willebrand factor, and is involved in platelet aggregation. CD51/CD61 complex has similar binding properties and is involved in modulating migration and survival of angiogenic endothelial cells.

    UniProt

    P05106

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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