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CD40 Ligand 抗体

CD40LG 适用: 人, 灵长类 FACS, ICC, IF, Func 宿主: 小鼠 Monoclonal 24-31 unconjugated
产品编号 ABIN5540106
发货至: 中国
  • 抗原 See all CD40 Ligand (CD40LG) 抗体
    CD40 Ligand (CD40LG)
    适用
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    人, 灵长类
    宿主
    • 87
    • 61
    • 21
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    • 1
    小鼠
    克隆类型
    • 108
    • 82
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    单克隆
    标记
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    This CD40 Ligand antibody is un-conjugated
    应用范围
    • 105
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    Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Functional Studies (Func)
    特异性
    This antibody detects CD154 / CD40L (CD40-ligand), a 39 kDa cell surface type II glycoprotein expressed predominantly on activated CD4+ lymphocytes.
    纯化方法
    Protein-A affinity chromatography (> 95% pure by SDS-PAGE)
    免疫原
    Human CD154 fusion protein
    克隆位点
    24-31
    亚型
    IgG1
    Top Product
    Discover our top product CD40LG Primary Antibody
  • 应用备注
    Flow cytometry. Immunocytochemistry. Functional application: blocking.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    95 % pure by SDS-PAGE) Buffer System: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    CD40 Ligand (CD40LG)
    别名
    cd154,cd40l (CD40LG 产品)
    别名
    CD154 antibody, cd40l antibody, CD40L antibody, HIGM1 antibody, IGM antibody, IMD3 antibody, T-BAM antibody, TNFSF5 antibody, TRAP antibody, gp39 antibody, hCD40L antibody, CD40-L antibody, Cd40l antibody, Ly-62 antibody, Ly62 antibody, Tnfsf5 antibody, CD40 ligand antibody, TNF superfamily member 5 antibody, CD40LG antibody, cd40l antibody, Cd40lg antibody
    背景
    CD154 / CD40L (CD40 ligand) is a member of the tumor necrosis factor family, and is expressed primarily on activated CD4+ lymphocytes, but also on mast cells, basophils, eosinophils and human dendritic cells. Its counter-receptor CD40 is expressed on antigen presenting cells, including dendritic cells, macrophages, and B cells, and also on fibroblasts. Triggering of CD40 by CD40L causes maturation of dendritic cells and upregulation of antigen presentation in functions of the MHC and costimulatory molecules. CD40L also functions as a direct stimulating factor for T cells. CD40L plays also roles e.g. in antibody class switching and modulation of apoptosis in the germinal center.
    UniProt
    P29965
    途径
    NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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