SETD8 抗体 (AA 220-249)
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北京 101111
Quick Overview for SETD8 抗体 (AA 220-249) (ABIN5537416)
抗原
See all SETD8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 220-249
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
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免疫原
- This SETD8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-249 amino acids from the Central region of human SETD8.
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亚型
- Ig Fraction
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应用备注
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For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 2 mg/mL
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缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- SETD8 (SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))
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别名
- SETD8
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背景
- SETD8 is a histone methyltransferase that specifically monomethylates 'Lys-20' of histone H4. H4 'Lys-20' monomethylation is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. It is required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNA during mitosis. It is also involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones.
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分子量
- 43 kDa
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基因ID
- 387893
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UniProt
- Q9NQR1
抗原
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