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CHMP4B 抗体 (N-Term)

This anti-CHMP4B antibody is a 兔 多克隆 antibody detecting CHMP4B in WB, FACS 和 IHC (p). Suitable for 人.
产品编号 ABIN5536006
发货至: 中国

Quick Overview for CHMP4B 抗体 (N-Term) (ABIN5536006)

抗原

See all CHMP4B 抗体
CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))

适用

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宿主

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克隆类型

  • 39
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多克隆

标记

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This CHMP4B antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 51-79, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This CHMP4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human CHMP4B.

    亚型

    Ig Fraction
  • 应用备注

    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:50~100

    For FACS starting dilution is: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))

    别名

    CHMP4B

    背景

    CHMP4B is a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies.

    分子量

    25 kDa

    基因ID

    128866

    UniProt

    Q9H444
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