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SIGLEC8 抗体 (C-Term)

Name: SIGLEC8 抗体 (C-Term)
SKU: ABIN5534688
Availability: OutOfStock

This anti-SIGLEC8 antibody is a 兔多克隆 antibody detecting SIGLEC8 in WB 和 IHC (p). Suitable for 人和小鼠.

Antibody is used in Western blot to detect Siglec8 in mouse liver tissue lysate (lnae 1) and in HL60 cell lysate (lane 2). (SIGLEC8 抗体 (C-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (SIGLEC8 抗体 (C-Term))

IHC

2 images

产品编号 ABIN5534688

发货至: 中国

Quick Overview for SIGLEC8 抗体 (C-Term) (ABIN5534688)

抗原

See all SIGLEC8 抗体

SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This SIGLEC8 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product SIGLEC8 Primary Antibody

抗原表位
7

6

3

3

2

2

2

2

1

1

1

1

1
AA 373-406, C-Term

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

免疫原

This SIGLEC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 373-406 amino acids from the C-terminal region of human SIGLEC8.

亚型

Ig Fraction
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (AA 18-121) antibody
SIGLEC8 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (AA 18-121) antibody
SIGLEC8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H1 unconjugated

anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (Internal Region) antibody
SIGLEC8 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (AA 70-336) antibody
SIGLEC8 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D3 unconjugated

anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (Internal Region) antibody
Verified SIGLEC8 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) antibody
SIGLEC8 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (Extracellular Domain) antibody
SIGLEC8 适用: 人 ELISA, IP, FACS 宿主: 小鼠 Monoclonal 7C9 unconjugated

anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (Extracellular Domain) antibody (PE)
SIGLEC8 适用: 人 FACS 宿主: 小鼠 Monoclonal 7C9 PE

anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (AA 17-363) antibody
SIGLEC8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (AA 70-336) antibody
SIGLEC8 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

限制

仅限研究用
状态

Liquid

浓度

1.67 mg/mL

缓冲液

Supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
抗原

SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))

别名

SIGLEC8

背景

SIGLEC8 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It preferentially binds to alpha2,3-linked sialic acid. and also binds to alpha2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. SIGLEC8 is expressed specifically on eosinophils. The protein contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in downmodulation of cellular responses. The phosphorylated ITIM motif binds to the SH2 domain of PTPN6/SHP-1. The SIGLEC8 gene belongs to the immunoglobulin superfamily.

分子量

54 kDa

基因ID

27181

UniProt

Q9NYZ4