SIGLEC8 抗体 (C-Term)
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Quick Overview for SIGLEC8 抗体 (C-Term) (ABIN5534688)
抗原
See all SIGLEC8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 373-406, C-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
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免疫原
- This SIGLEC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 373-406 amino acids from the C-terminal region of human SIGLEC8.
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亚型
- Ig Fraction
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anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (AA 18-121) antibody
SIGLEC8 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (AA 18-121) antibodySIGLEC8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H1 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (Internal Region) antibodySIGLEC8 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (AA 70-336) antibodySIGLEC8 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D3 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (AA 17-363) antibodySIGLEC8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (Internal Region) antibodyVerified SIGLEC8 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) antibodySIGLEC8 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (Extracellular Domain) antibodySIGLEC8 适用: 人 ELISA, IP, FACS 宿主: 小鼠 Monoclonal 7C9 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (Extracellular Domain) antibody (PE)SIGLEC8 适用: 人 FACS 宿主: 小鼠 Monoclonal 7C9 PE
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (AA 70-336) antibodySIGLEC8 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.67 mg/mL
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缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
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别名
- SIGLEC8
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背景
- SIGLEC8 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It preferentially binds to alpha2,3-linked sialic acid. and also binds to alpha2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. SIGLEC8 is expressed specifically on eosinophils. The protein contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in downmodulation of cellular responses. The phosphorylated ITIM motif binds to the SH2 domain of PTPN6/SHP-1. The SIGLEC8 gene belongs to the immunoglobulin superfamily.
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分子量
- 54 kDa
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基因ID
- 27181
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UniProt
- Q9NYZ4
抗原
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