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SIGLEC8 抗体 (N-Term)

This anti-SIGLEC8 antibody is a 兔 多克隆 antibody detecting SIGLEC8 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN5534687
发货至: 中国

Quick Overview for SIGLEC8 抗体 (N-Term) (ABIN5534687)

抗原

See all SIGLEC8 抗体
SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))

适用

  • 43
  • 6
  • 2

宿主

  • 28
  • 13
  • 1
  • 1

克隆类型

  • 30
  • 13
多克隆

标记

  • 30
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SIGLEC8 antibody is un-conjugated

应用范围

  • 33
  • 22
  • 16
  • 11
  • 10
  • 5
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 94-122, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This SIGLEC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-122 amino acids from the N-terminal region of human SIGLEC8.

    亚型

    Ig Fraction
  • 应用备注

    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))

    别名

    SIGLEC8

    背景

    Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM, MIM 603492) that mediates an association with SLAM-associated protein (SAP, MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).

    分子量

    54 kDa

    基因ID

    27181

    UniProt

    Q9NYZ4
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