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PAK4 抗体 (AA 187-216)

This 兔 多克隆 anti-PAK4 antibody specifically detects PAK4 in WB 和 FACS. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN5534399
发货至: 中国
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Quick Overview for PAK4 抗体 (AA 187-216) (ABIN5534399)

抗原

See all PAK4 抗体
PAK4 (P21-Activated Kinase 4 (PAK4))

适用

  • 76
  • 43
  • 25
  • 5
  • 5
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  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
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  • 1
人, 小鼠

宿主

  • 70
  • 5
  • 1

克隆类型

  • 68
  • 8
多克隆

标记

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  • 6
  • 5
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  • 3
  • 1
  • 1
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  • 1
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This PAK4 antibody is un-conjugated

应用范围

  • 59
  • 36
  • 21
  • 15
  • 12
  • 7
  • 7
  • 5
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS)
  • 抗原表位

    • 16
    • 8
    • 8
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 187-216

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This Mouse Pak4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of mouse Pak4.

    亚型

    Ig Fraction
  • 应用备注

    For WB starting dilution is: 1:1000

    For FACS starting dilution is: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    PAK4 (P21-Activated Kinase 4 (PAK4))

    别名

    Pak4

    背景

    Pak4 activates the JNK pathway. Plays a role in the reorganization of the actin cytoskeleton and in the formation of filopodia. Phosphorylates and inactivates the protein phosphatase SSH1, leading to increased inhibitory phosphorylation of the actin binding/depolymerizing factor cofilin. Decreased cofilin activity may lead to stabilization of actin filaments. Phosphorylates ARHGEF2 (By similarity).

    分子量

    65 kDa

    基因ID

    70584

    UniProt

    Q8BTW9

    途径

    RTK signaling
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