SSRP1 抗体 (C-Term)
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Quick Overview for SSRP1 抗体 (C-Term) (ABIN5533212)
抗原
See all SSRP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 490-518, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This SSRP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 490-518 amino acids from the C-terminal region of human SSRP1.
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亚型
- Ig Fraction
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应用备注
- For WB starting dilution is: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))
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别名
- SSRP1
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背景
- The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.
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分子量
- 81 kDa
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基因ID
- 6749
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UniProt
- Q08945
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途径
- Chromatin Binding
抗原
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